Doctor of Philosophy in Biomedical Sciences (2021/2022)
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1.  Introduction of Doctor of Philosophy in Biomedical Sciences Programme

The PhD programme aims to provide an in-depth knowledge and extensive specialized training in the area of biomedical sciences to students. Students, led by academic staff who are at professoriate ranks, engage in the independent scientific research in Biomedical Sciences and develop their dissertations. The research areas cover cancer precision medicine, stem cell and development, aging, neural and metabolism disorders, bioimaging, data science, drug development, neuropsychiatry, structural biology and translational medicine, and the normative study period of the programme is four years. In the first year of study, students take lecture courses such as Methodologies in Biomedical Sciences, Critical Scientific Reading, Writing and Analysis, Advanced Molecular Cell Biology, Research Ethics, which provide a solid foundation that assists them to carry out their research projects. In the second year, students are required to successfully pass the Qualifying Examination and Thesis Proposal Assessment. To complete the programme, students must finalize their dissertations and successfully pass the Oral Defence.

2.  Research Topic
Name of SupervisorResearch TopicsDetails
Prof. Chuxia DENG(1) Oncogenes and tumor suppressor genes
(2) Stem cells, cancer metastasis and drug development
Prof. Wei GE(1) Genetic analysis of growth and reproduction in the zebrafish model
(2) Impacts of environmental endocrine-disrupting chemicals (EDCs) on reproduction and public health
(3) Zebrafish as a model for aging, human diseases and drug discover
Prof. Han-Ming SHEN(1) Autophagy: regulatory mechanisms and biological functions in cancer
(2) Mitophagy: novel regulatory mechanisms
(3) Cancer metabolism: targeting glucose metabolism in lung cancer
Prof. Guokai CHEN
(1) Metabolic regulation in stem cell maintenance and differentiation
(2) Novel mechanisms involved in cardiomyocyte differentiation and maturation
(3) Skin cell differentiation for regenerative medicine
(4) Endoderm differentiation for disease model
PhD-adm_GKC
Prof. Edwin CHEUNG(1) Mechanism of gene regulation in cancer
(2) Single cell analysis
Prof. Kathy Qian LUO(1) Circulating tumor cells and cancer metastasis
(2) Drug resistant and anti-cancer drug discovery
Prof. San Ming WANGCancer genetic, hereditery breast cancer, genomics, bioinformatics
Prof. Garry WONGBioinformatics and computational biology of aging related neurodegenerative diseases
Prof. Yutao XIANG(1) Psychiatric epidemiology
(2) Health services research in psychiatry
(3) Evidence-based medicine in psychiatry
(4) COVID-19 related studies in psychiatry
(5) Cognition and psychiatric disorders
Prof. Ren-He XUMesenchymal stem cells: the development, heterogeneity, and assimilationPhD-adm_RHX
Prof. Xiaohua Douglas ZHANG(1) Digital medical research and data analysis
(2) Data mining for biomedical research
(3) Development of analytic software for high-throughput biomedical data
PhD-adm_DZ
Prof. Wenhua ZHENGFoxo and neuronal differentiation or new drugs development like artemisinin and metformin
Prof. William Chong Hang CHAOStructure and function of epigenetic regulatorsPhD-adm_WC
Prof. Lijun DI(1) Remodeling of transcriptional program in cancer development by both endogenous and exogenous factors via regulating CtBP status
(2) Molecular mechanism of cancer metastasis
(3) Investigating the molecular mechanisms and identifying the potential therapeutic targets of obesity and related disease
Prof. Hang Fai (Henry) KWOK(1) Antibody / venom-based peptide targeted therapy for anti-cancer prototype drug discovery & development
(2) Biomarkers identification and validation based on the hallmarks of cancer
Prof. Gang LI(1) Epigenetic mechanisms of tumorigenesis
(2) Signal transduction pathways in epigenetics
PhD-adm_GL
Prof. Tzu-Ming LIU(1) In vivo microscopy and spectroscopy of tumor microenvironment
(2) Develop serum fluoroscope for the diagnosis of organ function
Prof. Terence C.W. POON(1) Proteomics/protein/biomarker-based research in precision medicine
(2) Bioinformatics-based research in precision medicine
Prof. Joong Sup SHIMExploiting synthetic lethality for cancer target discovery
Prof. Kin Yip TAM(1) Development of small molecule inhibitors targeting cancer metabolism or Alzheimer’s disease
(2) Combined use of metabolic inhibitors in lung cancer models
(3) Chemical optimizations of small molecule inhibitors
Prof. Chris Koon Ho WONGTranscription regulation of fungal metabolism and infection.
Prof. Ruiyu XIE(1) Epigenetic regulation underlying cell fate determination
(2) Molecular switches in endodermal lineage specification
(3) Molecular mechanisms regulating proliferation and differentiation in the pancreas
Prof. Xiaoling XUBRCA1 associated breast cancer and cancer metastasis
Prof. Zhen YUAN(1) Neuroscience and neuroimaging
(2) Biomedical optics
(3) Optical molecular imaging and cancer nanomedicine
Prof. Xuanjun ZHANG(1) Fluorescent and photoacoustic probes for bioimaging/sensing
(2) Nanoreactors for biomedical applications
Prof. Wa Kam CHANG(1) How cells polarize during cell migration, with a focus on the cytoskeleton and nuclear envelope proteins
(2) How aging affects cell polarization and how cell polarization contributes to aging defects
(3) Characterize candidate aging factors and decipher their modes of action
Prof. Yunlu DAI(1) Cancer nanomedicine
(2) Molecular imaging
(3) Drug delivery
Prof. Leo Tsz On LEE(1) Small RNA-dendrimer in modulating the receptors in renin-angiotensin system to suppress cancer development and metastasis
(2) Proteomic and metabolic analyses of EPAC signaling in ovarian cancer
Prof. Ningyi SHAOCardiomyocytes differentiation across species
Prof. Vivien Ya-Fan WANGMechanism of gene regulation by NFkappaB and co-factors
Prof. Hongjie ZHANG(1) System-intrinsic sphingolipid homeostatic network regulation
(2) Molecular mechanisms of tubular organ morphogenesis
Prof. Qi ZHAO(1) Nanomedicine and target drug delivery
(2) Directed evolution of synthetic proteins and molecules
(3) Neutralizing antibodies against infections
Prof. Jun ZHENG(1) Type VI secretion system in pathogenic bacteria
(2) Development next generation antibiotics
(3) Bacterial persistence
3.  Application Instructions

Students are suggested to visit the faculty website and check the list of supervisors who are recruiting PhD students and their research topic(s). Students can contact the potential supervisor(s) directly for details if necessary. After selecting the supervisor, students who are interested in applying the PhD programme must submit the application through the online application system during the application period. Selected applicants will receive a notification about the interview arrangement by email. Students can submit applications through one of the following application channels:

Recommended Direct AdmissionApplicable to candidates who are recommended by one of the listed universities in Mainland China.
General EntryApplicable to candidates who possess a Master’s degree or academic background recognized as equivalent by the University of Macau.
Direct EntryApplicable to candidates who possess a Bachelor’s degree with outstanding performance and have demonstrated strong research ability.
Proof of English Proficiency
Applicants who received their Bachelor’s/Master’s degree from a university where the medium of instruction was not English are required to provide any of the following as proof of English proficiency:

  • Obtained a TOEFL* score of 550 (paper-based examination) / 80 (Internet-based examination) or above or,
  • An IELTS* overall score of 6.0 or above with no sub-score lower than 5.5 or,
  • College English Test (CET) score is acceptable to some academic units, please visit corresponding website of each academic unit for details.

*Note: TOEFL and IELTS scores are valid for two years from the test date.

4.  Application Period for 2021/2022 Academic Year
Recommended Direct Admission15 June 2020 to 13 August 2020 (First Batch)

14 August 2020 to 15 October 2020 (Second Batch)

General Entry / Direct Entry3 August 2020 to 29 October 2020 (First Batch)

30 October 2020 to 26 February 2021 (Second Batch)

5.   Financial Support to PhD Students
UM Macao PhD Scholarship (MPDS)The MPDS provides each awardee with a monthly stipend of MOP20,000 and a conference or research-related travel allowance up to MOP10,000 per academic year, for a period up to 4 years.
UM PhD AssistantshipThe Assistantship provides each new recipient with a starting monthly stipend of MOP12,500 (up to MOP14,000).

For details of the scholarship and assistantship, please refer to the “Guidelines for UM PhD Scholarship and Assistantship”.

6.   Accommodation

The Student Resources Section of the Student Affairs Office manages the Postgraduate House (PGH), which mainly offers on-campus accommodation and living services to UM postgraduate students. All the rooms in PGH are fully furnished and air-conditioned, excluding personal necessities and beddings (such as pillow, blanket, coverlet, bed sheet, etc.).

Contact

Email: FHS.Student@um.edu.mo

Tel: (853) 8822 4296 / 8822 4966

Click the following links to obtain more information:
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