Full publications
  1. Zhu L, Li P, Gao D, Liu J, Liu Y, Sun C. Xu M. Chen X, Sheng Z, Wang R. Yuan Z. Cai L, Ma Y, Zhao Q. pH-sensitive loaded retinal/indocyanine green micelles as a “all-in-one” theranostic agent for multi-modal imaging in vivo guided cellular senescence-photothermal synergistic therapy. Chemical Communications, 2019. 55 (44), 6209-6212

  2. Huang S1, Zhao Q1. Nanomedicine-combined immunotherapy for cancer. Current Medicinal Chemistry. 2019. 55 (44), 6209-6212

  3. Hu D, Zhu Z, Li S, Deng Y, Wu Y, Zhang N, Puri V, Wang C, Zou P, Lei C, Tian X, Wang Y, Zhao Q, Li W, Prabakaran P, Feng Y, Cardosa J, Qin C, Zhou X, Dimitrov DS, Ying T. A broadly neutralizing germline-like human monoclonal antibody against dengue virus envelope domain III. PLoS Pathogens. 2019 Jun 26;15(6):e1007836

  4. J Liu, G Zhou, L Zhang, Q Zhao, Building potent chimeric antigen receptor T cells with CRISPR genome editing. Frontiers in Immunology. 2019, 10: 456

  5. Shigao Huang, Chi Ian Fong, Mengze Xu, Bing-nan Han, Zhen Yuan, Qi Zhao. Nano-loaded natural killer cells as carriers of ICG for synergetic cancer immunotherapy and phototherapy. Journal of Innovative Optical Health Sciences. 2019. 12 (03), 1941002

  6. Yang-Hua Tang, Ting-Ting Liang, Ting-Ting Fan, Lawrence Jordan Keen, Xiao-Dan Zhang, Lin Xu, Qi Zhao, Rong Zeng, Bing-Nan Han. Neo-debromoaplysiatoxin C, with new structural rearrangement, derived from debromoaplysiatoxin. Natural product research, 2019: 1-6.

  7. Y Wang, Y Shan, X Gao, R Gong, J Zheng, XD Zhang, Q Zhao. Screening and expressing HIV-1 specific antibody fragments in Saccharomyces cerevisiae. Molecular immunology 2018. 103, 279-285.

  8. Gao H, Huang S, Du J, Zhang X, Jiang N, Kang W, Mao J, Zhao Q. Comparison of Prognostic Indices in NSCLC Patients with Brain Metastases after Radiosurgery. Int J Biol Sci 2018: 14(14):2065-2072.

  9. Wu Y, Chen Z, Zhang P, Zhou L, Jiang T, Chen H, Gong P, Dimitrov DS, Cai L, Zhao Q, Recombinant-fully-human-antibody decorated highly-stable far-red AIEdots for in vivo HER-2 receptor-targeted imaging. Chemical Communications. 2018. 54(53):7314-7317

  10. Li D, Yao G, Han B, Liu J, Su W, Wang P, Zhu Z, Dimitrov DS, Zhao Q, N-terminal α-amino group modification of antibodies using a site-selective click chemistry method. mAbs. 2018 10(5):712-719.

  11. Chen S, Li F, Ding Y, Wang D, Zhao Q, Wang Y, Zhou C, Wang Y, Andrographolide derivative as STAT3 inhibitor that protects acute liver damage in mice, Bioorganic & Medicinal Chemistry. 2018;26(18):5053-5061

  12. Liang T, Zhao Q, He S, Mu F, Deng W, Han B. Modeling Analysis of Potential Target of Dolastatin 16 by Computational Virtual Screening. Chemical and Pharmaceutical Bulletin. 2018. 6: 602-607.

  13. Hao D, Liu J, Chen M, Li J, Wang L, Wang G, Zhao Q, Di LJ,. Immunogenomic analyses of advanced serous ovarian cancer reveal immune score is a strong prognostic factor and an indicator of chemo-sensitivity. Clin Cancer Res. 2018 24(15):3560-3571

  14. Chen Z, Liu J, Chu D, Ma G, Zhang H, Shan Y, Chen Q, Deng C, Chen W, Dimitrov DS, Zhao Q, A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells. Int J Biol Sci 2018. 14(7):799-806

  15. Xie R, Zhang X, Zhao Q, Peng B, Zheng J. Analysis of global prevalence of antibiotic resistance in Acinetobacter baumannii infections disclosed a faster increase in OECD countries. Emerging Microbes & Infections 2018. 7:31 DOI 10.1038/s41426-018-0038-9.

  16. Li F, Li X, Sheng D, Chen S, Nie X, Liu Z, Wang D, Zhao Q, Wang Y,Wang Y, Zhou G. Discovery and preliminary SAR of 14-aryloxyandrographolide derivatives as antibacterial agents with immunosuppressant activity. RSC Adv. 2018, 8, 9440

  17. XuY,Li P, Nie J, Zhao Q, Guan S, Kuai , Qiao Y, Jiang X, Li Y, Li W, Shi Y, Kong W, Shan Y, Humanization and directed evolution of the selenium-containing scFv phage abzyme. RSC Adv., 2018,8, 17218-17223

  18. Kuai Z, Xu Y, Zhao Q, Liu J, Guan S, Qiao Y, Gong X, Nie J, Li P, Liu D, Xing Y, Li H, Sun Z, Wang W, Ning C, Shi Y, Kong W, Shan Y. Effects of insulin on transcriptional response and permeability in an in vitro model of human blood-brain barrier. J Cell Biochem. 2018. 119(7):5657-5664

  19. Han B, Liang T, Keen LJ, Fan T, Zhang X, Xu L, Zhao Q, Wang S, Lin H, Two Marine Cyanobacterial Aplysiatoxin Polyketides, Neo-debromoaplysiatoxin A and B, with K+ Channel Inhibition Activity. Organic Letters. 2018 Feb 2;20(3):578-581.

  20. Xu T, Ying T, Wang L, Zhang X, Wang Y, Kang L, Huang T, Cheng L, Wang L, Zhao Q. A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17A. Oncotarget. 2017.8 (47), 81860-81872

  21. Chen C, Jin Y, Lo I, Zhao H, Sun B, Zhao Q, Zhang XD Complexity Change in Cardiovascular Diseases. International Journal of Biological Sciences. 2017.13: 1320-1328

  22. Chu D, Dong X, Zhao Q, Gu J, Wang Z. Photosensitization priming of tumor microenvironments improves delivery of nanotherapeutics via neutrophil infiltration. Advanced Materials. 2017. 29(27). doi: 10.1002/adma.201701021

  23. Li D, Gong R, Zheng J, Chen X, Dimitrov D, Zhao Q, Engineered antibody CH2 domains binding to nucleolin: Isolation, characterization and improvement of aggregation. Biochemical and Biophysical Research Communications. 2017 (17): 30328-5.

  24. Chen Z, Wang L, Xu T, Wang Q, Kang L, Zhao Q. Generation of bispecific antibodies by Fc heterodimerization and their application. Current Pharmaceutical Biotechnology. 2016.17:1324-1332.

  25. Chu D, Zhao Q, Yu J, Zhang F, Zhang H, Wang J. Nanoparticle Targeting of Neutrophils for Improved Cancer Immunotherapy. Advanced Healthcare Materials, 2016.5(9):1088-93.

  26. Li D, Liu J, Zhang L, Xu T, Chen J, Wang L, Zhao Q. N terminal residues of an HIV-1 gp41 membrane-proximal external region antigen might hinder to direct neutralizing 2F5-like antibodies. Virologica Sinica, 2015.30: 449-456

  27. Ahmed M, Cheng M, Zhao Q, Guo H, Cheal S, Larson S, Cheung N. Humanized affinity-matured monoclonal antibody 8H9 has potent anti-tumor activity and binds to FG loop of B7-H3. Journal of Biological Chemistry, 2015.290 (50):30018-29.

  28. Zhang L, Chen J, Zhao Q. (2015) Regulatory Roles of Alu Transcript on Gene Expression Regulation. Experimental Cell Research. 2015.338(1):113-8.

  29. Zhao Q, Ahmed M, Guo H, Cheung IY, Cheung NK. Alteration of electrostatic surface potential enhances affinity and tumor killing properties of anti-GD2 monoclonal antibody hu3F8. Journal of Biological Chemistry. 2015.290:13017-13027

  30. Zhao Q, Ahmed M, Tassev DV,Hasan A, Kuo T, Guo H, O’Reilly RJ, Cheung NK. Affinity maturation of T-cell receptor-like antibodies for Wilms tumor 1 peptide greatly enhances therapeutic potential. Leukemia. 2015.29(11):2238-2247

  31. Zhao Q, Tran H, Dimitrov DS, Cheung NK. (2015) A dual specific anti-IGF-1/IGF-2 human monoclonal antibody alone and in combination with temsirolimus for therapy of neuroblastoma. International Journal of Cancer. 2015.137:2243-2252

  32. Leung SO, Gao K, Wang GY, Cheung BK, Lee KY, Zhao Q, Cheung WT, Wang JZ. Surrogate target cells expressing surface anti-idiotype antibody for the clinical evaluation of an internalizing CD22-specific antibody. mAbs. 2015.7(1):66-76

  33. Feng Y, Zhao Q, Chen W, Wang Y, Crowder K, Dimitrov DS, A new bispecific antibody targeting non-overlapping epitopes on IGF2: Design, in vitro characterization and pharmacokinetics in macaques. Experimental and Molecular Pathology 2014.97: 359-67

  34. Zhao Q, Wong PF, Lee ST, Cheung WT, Leung RO, Wang JZ, Generation of anti-idiotype scFv for pharmacokinetic measurement in lymphoma patients treated with chimera anti-CD22 antibody SM03, PLOS One. 2014.9(5): e96697

  35. Zhang R, Zhang CY, Zhao Q, Li DH, Spectrin: Structure, function and disease, SCIENCE CHINA-Life Sciences 2013.12: 1076–1085

  36. Zhao Q., Zhu Z., Dimitrov D. Yeast display of engineered antibody domain. Methods in Molecular Biology, 2012.899: 73-84

  37. Chen W, Feng Y, Zhao Q, Zhu Z, Dimitrov D. Human monoclonal antibodies targeting nonoverlapping epitopes on insulin-like growth factor II as a novel type of candidate cancer therapeutics. Molecular Cancer Therapeutics 2012.11 (7): 1400-10

  38. Zhao Q., Feng Y., Zhu Z., Dimitrov D. Human monoclonal antibodies to IGF1/2 with picomolar affinity. Molecular Cancer Therapeutics, 2011.10(9); 1677-85

  39. Cheng M., Chan S., Zhao Q., Chan E., Au S., Lee S., Cheung W.T., Construction and Characterization of Single-chain Variable Fragment Antibody Library Derived from Germline Rearranged Immunoglobulin Variable Genes. PLOS One 2011.6(11): e27403

  40. Chen W., Feng Y., Zhu Z., Zhao Q., Dimitrov D. Engineered single human CD4 domains as potent HIV-1 inhibitors and components of vaccine immunogens. Journal of Virology, 2011.85 (18): 9395-405

  41. Gong R., Wang Y., Feng Y., Zhao Q., Dimitrov D. Shortened Engineered Human Antibody CH2 Domains: Increased Stability and Binding to the Human Neonatal Receptor. Journal of Biological Chemistry, 2011.286(31): 27288-93

  42. Zhu Z., Qin H., Chen W., Zhao Q., et al. Cross-reactive HIV-1-neutralizing human monoclonal antibodies identified from a patient with 2F5-like antibodies. Journal of Virology, 2011.85(21)11401-8

  43. Zhao Q., Chan Y.W., Lee S.S., Cheung W.T. One-step expression and purification of single-chain variable antibody fragment using an improved hexahistidine tag phagemid vector. Protein Expression and Purification, 2009.68(2):190-5.

  44. Cheng M., Chan C.W., Cheung R.C., Bikkavilli R.K., Zhao Q., Au S.W., Chan P.K., Lee S.S., Cheng G., Ho W.K. and Cheung W.T.. Cross-reactivity of antibody against SARS-coronavirus nucleocapsid protein with IL-11. Biochemical and Biophysical Research Communications 2005.338: 1654-60.

  45. Liu J., Zhao Q., Zhao B., Cheng J., Wang X., Song L., Zhang Z., Lin Q. and Huang H. A new format of single chain tri-specific antibody with diminished molecular size efficiently induces ovarian tumor cell killing. Biotechnology Letters 2005. 27: 1821-7.

  46. Wang X.B., Zhao B.F., Zhao Q., Piao J.H., Liu J., Lin Q. and Huang H.L. A new recombinant single chain trispecific antibody recruits T lymphocytes to kill CEA (carcinoma embryonic antigen) positive tumor cells in vitro efficiently. Journal of Biochemistry 2004.135: 555-65.

  47. Liu J, Wan X, Lv W, Li J, Zhao Q. (2015) Research Progress of microRNA in Revention and Treatment of Non-small Cell Lung Cancer. Progress in Modern Biomedicine. 10: 1966-70, Chinese

  48. Tian Y, Chen F, Liu J, Zou J, Wan X, Zhao Q, (2015) The Progression of Neuroblastoma Treatment with Immunotherapy, Progress in Modern Biomedicine, 10: 1973-04, Chinese

  49. Liu J, Chen J, Xu T, Wang L, Zhao Q. (2014) Construction of a large human Fab phage display antibodies library and screening of phage antibodies against CD276. Chinese Medicinal Biotechnology. 4:273-77, Chinese