Contact Information 
Address(Office)E12-3023 Jung Woo Park
Phone(Office)8822 4225
(Lab)8822 2908
Fax8822 2314
Ph.D.Michigan State University
B.S.Michigan State University
2014-presentSenior Instructor, Faculty of Health Sciences, University of Macau
2008-2014Research Scientist, Stem Cell Institute, UConn Health Center
2003-2008Post-doctoral Fellow, UConn Health Center
Research Interests
  • Molecular circuitry of induced Pluripotent Stem Cells (iPSC) reprogramming
  • Molecular mechanisms for Marfan Syndrome (MS), a genetic disease manifested in defects of mesenchymal lineages and connective tissues
  • Regulatory mechanisms by which human Embryonic Stem Cells (hESCs) differentiate into Mesenchymal Stem Cells (MSCs)
  • Post-transcriptional regulations in hESC/iPSC self-renewal and differentiation
Representative Publications
  • Li, E., Zhang, Z., Jiang, B., Yan, L., Park, J.W., and Xu, R.-H. Generation of mesenchymal stem cells from human embryonic stem cells in a complete serum-free condition. Int’ l J. Biol. Sci. 14(13):1901-9, 2018
  • Yang, J., Park, J.W., Zheng, D., and Xu, R.-H. Universal corneal epithelial-like cells derived from human embryonic stem cells for cellularization of a corneal scaffold. Trans’l Vision Sci. & Technol. 7(5):23. 2018
  • Yan L., Jiang B., Li E.Q., Wang X.Y., Ling Q., Zheng D.J., Park J.W., Chen X., Cheung E., Du X., Li Y.C., Cheng G., He E.X. Xu R.H., 2018 Scalable Generation of Mesenchymal Stem Cells from Human Embryonic Stem Cells in 3D. Int. J. Biol. Sci.:14(10):1196-1210, 2018
  • Park J.W.#, Yang J., Xu R.H., PAX6 alternative splicing and corneal development. Stem Cells and Development, 27(6):367-377, 2018
  • Park J.W., Yan L., Stoddard C., Wang X.F., Yue Z.C., Crandall L., Robinson T., Chang Y.X., Denton K., Li E.Q., Jiang B., Zhang Z.W., Martins-Taylor K., Yee S.P., Yue L.X., Xu, R.H.,  Recapitulating and correcting Marfan Syndrome in a cellular model.Int J Biol Sci, 13(5):588-603, 2017
  • Wang, J.*, Park, J.W.*, Drissi, H., Wang, X., and Xu, R.-H. Epigenetic Regulation of miR-302 by JMJD1C Inhibits Neural Differentiation of Human Embryonic Stem Cells. J. Biol. Chem. 289(4):2384-95, 2014
  • Brooks A.N., Yang L., Duff M.O., Hansen K.D., Park J.W., Dudoit S., Brenner S.E. Graveley B.R. 2011 Conservation of an RNA Regulatory Map Between Drosophila and Mammals. Genome Research, 21(2):193-202
  • Zeng H., Guo M., Martins-Taylor K., Wang X., Zhang Z., Park J.W., Zhan S., Kronenberg M.S., Lichtler A., Liu H.-X., Chen F.-P., Yue L., Li, X.-J., Xu R.-H. 2010 Specification of Region-specific Neurons Including Forebrain Glutamatergic Neurons From Human Induced Pluripotent Stem Cells.  PLoS ONE 5(7):e11853, 2010
  • Zeng H., Park J.W., Guo M., Lin G., Li X., Chen F., Xu R.H. 2009. Lack of ABCG2 Expression and Side Population Properties in Human Pluripotent Stem Cells. Stem Cells, 27(10):2435-45
  • Voss P.G., Gray R.M., Dickey S.W., Wang W., Park J.W., Kasai K.I., Hirabayashi, J., Patterson R.J., and Wang J.L. 2008.   Dissociation of the carbohydrate-binding and splicing activities of galectin-1.  Arch Biochem Biophys, 478(1):18-25. Epub 2008 Jul 16.
  • Olson S., Blanchette M., Park J.W., Savva Y., Yeo G., Yeakley J., Rio D., and Graveley  B.R.  2007.  A regulator of Dscam mutually exclusive splicing fidelity. Nature Struct and Mol Biol, 14:1134 – 1140
  • Yang L., Park J.W., and Graveley B.R. 2007.  Splicing from the outside in.  Molecular Cell, 27:861-2
  • Park J.W. and Graveley B.R. 2007. Complex alternative splicing. In Alternative splicing in the postgenomic era. edited by Graveley B.R. and Blencowe B. Eurekah Biosciences. 50-63.
  • Wang W.*, Park J.W.*, Wang J.L., and Patterson R.J. 2006.  Immunoprecipitation of spliceosomal RNAs by antisera to galectin1-1 and galectins-3 (*equal contribution).  Nucleic Acids Res, 34:5166-74
  • Park J.W. and Graveley, B.R. 2005.  The use of RNA interference to dissect the roles of trans-acting factors in alternative pre-mRNA splicing.  Methods  37:341-4
  • Philips D.L., Park J.W. and Graveley B.R.  2004.  A computational and experimental approach towards a priori identification of alternatively spliced exons.  RNA, 10:1838-1844. Epub 2004 Nov 3
  • Park J.W., Parisky K., Celotto A., Reenan R.A., and Graveley B.R.  2004.  Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci USA, 101:15974-15979. Epub 2004 Oct 18.
  • Park J.W., Voss P., Grabski S., Wang J.L., and Patterson R.J.  2001.  Association of galectins-1 and galectins-3 with Gemin4 in complexes containing the SMN protein.  Nucleic Acids Res, 27(17):3595-3602
  • Patterson R.J., Park J.W., and Wang J.L. 2001.  Intracellular functions of galectins.  Recent Res. Dev. Mol. Cell. Biol., 2:233-245