哲學博士(生物醫藥)課程

課程簡介

生物醫學科學家填補了基礎科學與醫學之間的空隙,開展研究以了解人類疾病,努力尋求改善人類健康的方法。本哲學博士(生物醫藥)課程給予有興趣的學生一個機會在教授級別的學術人員指導下,從事獨立研究工作及撰寫研究論文。本課程旨在培育有志從事生物學與生物醫學科學研究的學生,成為生物醫學科學領域中傑出的科研人員。

研究方向

課程內容

正常修讀期

4年

招生訊息

2022/2023學年招生詳情
導師名稱研究主題
鄧初夏教授Oncogenes and tumor suppressor genes
Stem cells, Cancer metastasis and Drug development
葛偉教授Genetic analysis of growth and reproduction in the zebrafish model
Impacts of environmental endocrine-disrupting chemicals (EDCs) on reproduction
and public health
Zebrafish as a model for aging, human diseases and drug discovery
沈漢明教授Autophagy: Regulatory mechanisms and biological functions in cancer
Mitophagy: Novel regulatory mechanisms
Cancer metabolism: Targeting glucose metabolism in lung cancer
徐仁和教授Mesenchymal stem cells: the development, heterogeneity, functions,
and therapeutic application
陳國凱教授Metabolic regulation in stem cell maintenance and differentiation
Novel mechanisms involved in cardiomyocyte differentiation and maturation
Skin cell differentiation for regenerative medicine
Endoderm differentiation for disease model
張仲榮教授Mechanism of gene regulation in cancer
Single cell analysis
羅茜教授Circulating tumor cells and cancer metastasis
Drug resistant and anti-cancer drug discovery
黃值富教授Bioinformatics and Computational Biology of Aging related
neurodegenerative diseases
項玉濤教授Psychiatric epidemiology
Health services research in psychiatry
Evidence-based medicine in psychiatry
COVID-19 related studies in psychiatry
Cognition and psychiatric disorders
張曉華教授High throughput sequencing studies and data analysis
Data mining for biomedical research
Development of analytic software for high-throughput biomedical data
鄭文華教授Foxo and neuronal differentiation or new drugs development
like artemisinin and metformin
Drug development
Neurodegenerative diseases
The effect of Chinese medicine on tumor growth/metastasis
and their underlying mechanisms 
周昶行教授Structure and Function of Epigenetic Regulators
狄利俊教授Remodeling of transcriptional program in cancer
development by both endogenous and exogenous
factors via regulating CtBP status
Molecular mechanism of cancer metastasis
Investigating the molecular mechanisms and identifying
the potential therapeutic targets of obesity and related disease
郭珩輝教授Antibody / Venom-based peptide targeted therapy for anti-cancer
prototype drug discovery & development (Novel multi-specific
antibody platforms for immunotherapy; Novel protein expression
system for large scale production of hard-to-express venom-based
protein drugs
Biomarkers identification and validation based on the hallmarks
of cancer
Tackling cancer metastasis and drug resistance: from mechanism
to therapy (Glyco-engineering to improve antibody quality
attibutes for cancer therapy)
李剛教授Cancer epigenetics: from mechanism to therapy
Signal transduction pathways in Epigenetics
劉子銘教授In vivo microscopy and spectroscopy of tumor microenvironment
Develop serum fluoroscope for the diagnosis of organ function
潘全威教授Proteomics/Protein/Biomarker-based research in precision medicine
Bioinformatics-based research in precision medicine
沈仲燮教授Exploiting synthetic lethality for cancer target discovery
譚建業教授Development of small molecule inhibitors targeting cancer
metabolism or Alzheimer’s disease
Combined use of metabolic inhibitors in lung cancer models
黃冠豪教授Transcription regulation of fungal metabolism and infection.
Identification of novel fungal secondary metabolites with
anti-cancer and antibiotic properties.
Understanding the regulation of fungal spore dormancy
and germination.
謝瑞瑜教授Develop transplantable platform for stem-cell based diabetic therapy
Molecular switches in endodermal lineage specification
Epigentic regulation shapping tumor immune microenvironment
in pancreas
徐曉玲教授BRCA1 associated breast cancer and cancer metastasis
袁振教授Neuroscience and neuroimaging
Biomedical Optics
Optical Molecular Imaging and Cancer Nanomedicine
張宣軍教授Molecular probes for imaging/sensing and diagnosis
Design of nanoreactors for biomedical applications
曾華鑫教授How cells polarize during cell migration, with a focus on the
cytoskeleton and nuclear envelope proteins
How aging affects cell polarization and how cell polarization
contributes to aging defects
Deciphering the acting mechanism of aging factors on the
cellular and whole genome levels
代雲路教授Cancer nanomedicine
Molecular imaging
Drug delivery
李子安教授Explore the role of GPCR biased signalling in cancers
Proteomic and metabolic analyses of EPAC signaling in cancer cells
邵寧一教授Study of lncRNA regulation in gender-biased diseases
Integrated multi-omics analysis of tumor microevolution at the
single cell level
王雅凡教授Mechanism of gene regulation by NFkappaB and co-factors
張紅杰教授Deciphering the mRNP code in epithelial morphogenesis
Post-translational modification in tubular organ formation
Sphingosine 1-phosphate signaling in lumenal membrane integrity
趙琦教授Nanomedicine and target drug delivery
Antibody-based therapeutics against tumors
鄭軍教授Type VI Secretion System in Pathogenic bacteria
Development next generation antibiotics
Bacterial persistence
陳強教授Molecular mechanisms of cancer development
Regulation of metabolic homeostasis
Mechanisms of drug resistance in cancer

聯絡

學業指導老師 鄧初夏教授, 研究生課程委員會主席

電郵: cxdeng@um.edu.mo

陳國凱教授, 副院長(教學)

電郵: guokaichen@um.edu.mo

行政支援(招生事務) 任先生

電郵: davidren@um.edu.mo

行政支援(課程事務) 吳小姐

電郵: stephaniepwng@um.edu.mo