Talk title | Intravital imaging and micromanipulation of stem cell niches in bone |
Speaker | Prof. Charles LIN Associate Professor Wellman Center for Photomedicine Massachusetts General Hospital Havard Medical School |
Date & Time | 08 November 2018 (Thurs) 11:00am-12:00pm |
Venue | Room G004, E12 Building (University of Macau) |
Abstract | We are developing optical techniques to study the bone and the bone marrow, a rich source of stem cells including hematopoietic stem cells (HSCs) and mesenchymal stem cells (MSCs). HSCs are responsible for the sustained regeneration of all blood cells after bone marrow transplantation. In addition, the sutures between cranial bones contain a population of skeletal stem cells (SSCs) that are capable of bone regeneration. Intravital microscopy and laser micromanipulation are used to gain deeper insights into the biology of HSCs and SSCs in their native microenvironment. |