| Talk title | The Therapeutic Window of Stroke Treatment |
| Speaker | Prof. John H. ZHANG Professor Departments of Anesthesiology, Physiology, Neurosurgery and Neurology, Loma Linda University School of Medicine |
| Date & Time | 04 Sep 2019 (Wed) 15:00-16:00 |
| Venue | Room G004, E12 Building (University of Macau) |
| Abstract | Stroke is a leading cause of death and disability especially for Chinese population. The current treatment strategy is to recanalize or to re-open the clotted blood vessels within a few hours named therapeutic window, Some called it “time is brain”. But because most researchers believe stroke penumbra only survives for a few hours, the majority of stroke patients are not in the therapeutic window and therefore most stroke patients are not treated by this strategy. This presentation will analyze the pathophysiology of stroke penumbra, its origination, definition, and progression, and proposes a new strategy called delayed recanalization, could be days, weeks or months after a stroke event. Experimental data and some clinical case studies demonstrated that delayed recanalization improved neurological function by rescuing penumbra tissues and especially by correction of hypoperfusion status of the hemisphere. The delayed recanalization has potentials to improve neurological function for the majority of stroke patients. |