Talk title | Definitive elucidation of virulence mechanisms: Lessons from Campylobacter for understanding why bacteria cause disease |
Speaker | Prof. Swaine CHEN Assistant Professor, National University of Singapore Yong Loo Lin School of Medicine |
Date & Time | 15 August 2017 (Tuesday) 10:00-11:00 |
Venue | Room G003, E12 Building (University of Macau) |
Abstract | Despite dramatic advances in sequencing and associated techniques, the central challenge for understanding infections has remained. Why does a given bacteria cause disease? We collaborated to develop both experimental and computational methods for understanding why Campylobacter jejuni recently became a worrying cause of infection-associated abortion in sheep in the US. This project offers clear lessons for understanding why other bacteria are able to cause disease and conceptually unites two other major efforts in the lab: the development of better genetic tools for E. coli and the sequence analysis of bacterial outbreaks. Through these I hope to share with you a glimpse of the genomics promise for infectious disease in the coming years. |