Talk title | Molecular mechanisms of the type VI protein secretion system – a deadly microbial weapon |
Speaker | Prof. Tao DONG Associate Professor University of Calgary |
Date & Time | 13 November 2018 (Fri) 10:00am-11:00am |
Venue | Room G004, E12 Building (University of Macau) |
Abstract | In complex microbial communities, microbes often rely on their antimicrobial systems as a survival tool to compete against other neighbouring species. Such antagonistic interaction can determine the dynamic changes or homeostasis of a community. The type VI protein secretion system (T6SS) is known to deliver antimicrobial effectors to target cells and is a common weapon of gram-negative bacteria. In our study, we use biochemical and imaging tools to investigate the mechanism of T6SS assembly and function, and its impact on community structure. |