| Talk title | Reprogramming Metabolomics |
| Speaker | Prof. Xuanxian PENG Professor School of Life Sciences, Sun Yat-sen University |
| Date & Time | 29 Oct 2019 (Tue) 15:00-16:00 |
| Venue | Room G003, E12 Building (University of Macau) |
| Abstract | Metabolomics is emerging as a powerful tool for studying metabolic processes, identifying crucial biomarkers responsible for metabolic characteristics, and revealing metabolic mechanisms, which construct the content of discovery metabolomics. The crucial biomarkers can be used to reprogram a metabolome, leading to an aimed metabolic strategy to cope with alteration of internal and external environments. Prof. PENG have termed it reprogramming metabolomics. They show that antibiotic-resistant metabolome can be reprogrammed to antibiotic-sensitive metabolome in bacteria and infective metabolome to anti-infective metabolome in host. Therefore, the reprogramming metabolome can elevate the sensitivity of antibiotic-resistant bacteria to antibiotics and restore host’s ability against bacterial infection. In summary, the reprogramming metabolomics will provide an alternative way for prevention and treatment of diseases. |