The 1st Macau-Mainland China Symposium on Biophotonics 2018 was successfully held in UM on 2 May 2018 as an annual event in alternating Macau and Mainland China. This symposium was presided by Prof. Zhen YUAN from the Faculty of Health Sciences (FHS) of the University of Macau and Prof. Junle QU from Shenzhen University. In the opening ceremony, Prof. Chuxia DENG, Dean of FHS, delivered a welcoming speech. Through the symposium, the close partnership between Mainland and Macau is perfectly established in the field of biophotonics to accelerate this promising scientific collaboration in research and education.