| Talk title | Establishment and Maintenance of Epigenetic Information |
| Speaker | Prof. Bing Zhu Investigator, Deputy Director Institute of Biophysics, Chinese Academy of Sciences |
| Date & Time | 23 Aug 2019 (Fri) 11:00-12:00 |
| Venue | Room G004, E12 Building (University of Macau) |
| Abstract | Dr. ZHU is currently the vice director and a principal investigator of the Institute of Biophysics, Chinese Academy of Science. He got his B.S. degree from Zhejiang University and his Ph.D. degree from Shanghai Institute of Plant Physiology, Chinese Academy of Sciences. Dr. ZHU’s research studies how epigenetic information is passed between generations of cells. As the corresponding author, he published scientific papers in high-impact journals, such as Nature, Science, Molecular Cell, Genes & Development, PNAS, EMBO J, etc. His research is highly recognized in the scientific community, and won prestigious awards such as the International Early Career Scientist award from Howard Hughes Medical Institute (2012), the C. C. Tan Life Science Research Award (2014) and the Chinese Distinguished Young Scientist Award (2014)
DNA methylation-mediated silencing and the establishment of DNA methylation are classic epigenetic events. Despite of a large body of studies in these directions, many unknown regulations exist. Recently, Dr. ZHU’s team performed a number of cell-based large scale screenings to identify novel regulators involved in DNA methylation-mediated silencing and the establishment of DNA methylation. He will report their findings highlighting mechanisms controlling the establishment of DNA methylation during oocyte maturation. In addition, he will present an unpublished story regarding the kinetics, fidelity control mechanisms, and functional implications of maintenance DNA methylation. |