Talk titlePrion-like dissemination of synuclein pathology using human brain-derived alpha-synuclein in monkeys
Speaker Dr. Erwan Bezard
Research Director
University of Bordeaux
Date & Time16 January 2019 (Wed)
15:00-16:00
VenueRoom G004, E12 Building (University of Macau)
AbstractUsing multidisciplinary approaches involving functional anatomy, biochemistry and molecular biology, we try to understand the mechanisms responsible for hypokinesia feature of parkinsonian syndromes, its response to L-Dopa and its complications such as dyskinesias Dopa-induced (DDI), as well as the mechanisms leading to neuronal death in these disorders. Our work involves analysis of the behavior and brain of rodents, non-human and human primate to establish correlations.