1. Karahoda, B., Pardeshi, L., Ulas, M., Dong, Z., Shirgaonkar, N., Guo, S., Wang, F., Tan, K., Sarikaya-Bayram, O., Bauer, I., Fleming , A.B., Pfannenstiel, B., Graessle, S., Alhussain, M., Strauss, J., Keller, N., Wong, K. H., and Bayram, O., KERS. A novel chromatin complex controls development and mycotoxin synthesis in Aspergillus nidulans. Science Advances (Submitted)
  2. Wang, F., Sethiya, P., Hu, X., Tan, K., and Wong, K. H.. Fungal spore experience before dormancy matters. Nature Microbiology (Submitted)
  3. Li, A, Parsania, C, Tan, K., Todd, R, and Wong, K. H.. Fungal co-option of an insect protease gene for extracellular nutrient degradation and transcriptional control.. Communications Biology (Submitted)
  4. Lyu, J. F., Yang, E. J., Zhang, B. Y., Wu, C. J., Pardeshi, L., Shi, C. X., Mou, P. K., Liu, Y. F., Tan, K., and Shim, J. S. (2020) Synthetic lethality of RB1 and aurora A is driven by stathmin-mediated disruption of microtubule dynamics. Nature Communications 11(1), 5105
  5. Liu, J. L., Adhav, R., Miao, K., Su, S. M., Mo, L. H., Chan, U. I., Zhang, X., Xu, J., Li, J. J., Shu, X. D., Zeng, J. M., Zhang, X., Lyu, X., Pardeshi, L., Tan, K., Sun, H., Wong, K. H., Deng, C. X., and Xu, X. L. (2020) Characterization of BRCA1-deficient premalignant tissues and cancers identifies Plekha5 as a tumor metastasis suppressor. Nature Communications 11(1), 4875
  6. Zhou, P., Chan, B. K. C., Wan, Y. K., Yuen, C. T. L., Choi, G. C. G., Li, X., Tong, C. S. W., Zhong, S. S. W., Sun, J., Bao, Y., Mak, S. Y. L., Chow, M. Z. Y., Khaw, J. V., Leung, S. Y., Zheng, Z., Cheung, L. W. T., Tan, K., Wong, K. H., Chan, H. Y. E., and Wong, A. S. L. (2020) A Three-Way Combinatorial CRISPR Screen for Analyzing Interactions among Druggable Targets. Cell Reports 32(6), 108020
  7. Ries, L. N. A., Pardeshi, L., Dong, Z., Tan, K., Steenwyk, J. L., Colabardini, A. C., Ferreira Filho, J. A., de Castro, P. A., Silva, L. P., Preite, N. W., Almeida, F., de Assis, L. J., Dos Santos, R. A. C., Bowyer, P., Bromley, M., Owens, R. A., Doyle, S., Demasi, M., Hernandez, D. C. R., Netto, L. E. S., Pupo, M. T., Rokas, A., Loures, F. V., Wong, K. H., and Goldman, G. H. (2020) The Aspergillus fumigatus transcription factor RglT is important for gliotoxin biosynthesis and self-protection, and virulence. Plos Pathogens 16(7), e1008645
  8. Miao, K., Lei, J. H. P., Valecha, M. V., Zhang, A. P., Xu, J., Wang, L. J., Lyu, X. Y., Chen, S., Miao, Z. Q., Zhang, X., Su, S. M., Shao, F. Y., Rajendran, B. K., Bao, J. L., Zeng, J. M., Sun, H., Chen, P., Tan, K., Chen, Q., Wong, K. H., Xu, X. L., and Deng, C. X. (2020) NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation. Nature Communications 11(1), 3256
  9. Sethiya, P., Rai, M. N., Rai, R., Parsania, C., Tan, K., and Wong, K. H. (2020) Transcriptomic analysis reveals global and temporal transcription changes during Candida glabrata adaptation to an oxidative environment. Fungal Biology 124(5), 427-439
  10. Zhang, B. Y., Lyu, J. F., Yang, E. J., Liu, Y. F., Wu, C. J., Pardeshi, L., Tan, K., Chen, Q., Xu, X. L., Deng, C. X., and Shim, J. S. (2020) Class I histone deacetylase inhibition is synthetic lethal with BRCA1 deficiency in breast cancer cells. Acta Pharm Sin B 10(4), 615-627
  11. Choi, G. C. G., Zhou, P., Yuen, C. T. L., Chan, B. K. C., Xu, F., Bao, S., Chu, H. Y., Thean, D., Tan, K., Wong, K. H., Zheng, Z. L., and Wong, A. S. L. (2019) Combinatorial mutagenesis en masse optimizes the genome editing activities of SpCas9. Nature Methods 16(8), 722-730
  12. Qin, L. G., Li, A., Tan, K., Guo, S. h., Chen, Y. Y., Wang, F., and Wong, K. H. (2019) Universal plasmids to facilitate gene deletion and gene tagging in filamentous fungi. Fungal Genetics And Biology 12528-35
  13. Tan, K., and Wong, K. H. (2019) RNA polymerase II ChIP-seq-a powerful and highly affordable method for studying fungal genomics and physiology. Biophysical Reviews 11(1), 79-82
  14. Liu, Y., Yang, E. J., Zhang, B. Y., Miao, Z. Q., Wu, C. J., Lyu, J. F., Tan, K., Poon, T. C. W., and Shim, J. S. (2018) PTEN deficiency confers colorectal cancer cell resistance to dual inhibitors of FLT3 and aurora kinase A. Cancer Letters 43628-37
  15. Zhang, B. Y., Lyu, J. F., Liu, Y. F., Wu, C. J., Yang, E. J., Pardeshi, L., Tan, K., Wong, K. H., Chen, Q., Xu, X. l., Deng, C. X., and Shim, J. S. (2018) BRCA1 deficiency sensitizes breast cancer cells to bromodomain and extra-terminal domain (BET) inhibition. Oncogene 37(49), 6341-6356
  16. Veri, A., Miao, Z. Q., Shapiro, R., Tebbji, F., O’Meara, T., Kim, S. H., Colazo, J., Tan, K., Vyas, V., Whiteway, M., Robbins, N., Wong, K. H., and Cowen, L. (2018) Tuning Hsf1 levels drives distinct fungal morphogenetic programs with depletion impairing Hsp90 function and overexpression expanding the target space. Plos Genetics 14(3), e1007270
  17. Xie, J. L., Qin, L. G., Miao, Z. Q., Grys, B., Diaz, J. D. L. C., Ting, K., Krieger, J., Tong, J. F., Tan, K., Leach, M., Ketela, T., Moran, M., Krysan, D., Boone, C., Andrews, B., Selmecki, A., Wong, K. H., Robbins, N., and Cowen, L. (2017) The Candida albicans transcription factor Cas5 couples stress responses, drug resistance and cell cycle regulation. Nature Communications 8(1), 499
  18. Leach, M. D., Farrer, R. A., Tan, K., Miao, Z., Walker, L. A., Cuomo, C. A., Wheeler, R. T., Brown, A. J., Wong, K. H., and Cowen, L. E. (2016) Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans. Nature Communications 711704
  19. Downes, D. J., Chonofsky, M., Tan, K., Pfannenstiel, B. T., Reck-Peterson, S. L., and Todd, R. B. (2014) Characterization of the mutagenic spectrum of 4-nitroquinoline 1-oxide (4-NQO) in Aspergillus nidulans by whole genome sequencing. G3-Genes Genomes Genetics 4(12), 2483-2492
  20. Tan, K., Roberts, A. J., Chonofsky, M., Egan, M. J., and Reck-Peterson, S. L. (2014) A microscopy-based screen employing multiplex genome sequencing identifies cargo-specific requirements for dynein velocity. Molecular Biology Of The Cell 25(5), 669-678
  21. Egan, M. J., Tan, K., and Reck-Peterson, S. L. (2012) Lis1 is an initiation factor for dynein-driven organelle transport. Journal Of Cell Biology 197(7), 971-982
  22. Zhang, J., Tan, K., Wu, X., Chen, G., Sun, J., Reck-Peterson, S. L., Hammer, J. A., 3rd, and Xiang, X. (2011) Aspergillus myosin-V supports polarized growth in the absence of microtubule-based transport. Plos One 6(12), e28575
  23. Pal, B., Chan, N. C., Helfenbaum, L., Tan, K., Tansey, W. P., and Gething, M. J. (2007) SCFCdc4-mediated degradation of the Hac1p transcription factor regulates the unfolded protein response in Saccharomyces cerevisiae. Molecular Biology Of The Cell 18(2), 426-440
  24. Oon, C. J., Chen, W. N., Goh, K. T., Mesenas, S., Ng, H. S., Chiang, G., Tan, C., Koh, S., Teng, S. W., Toh, I., Moh, M. C., Goo, K. S., Tan, K., Leong, A. L., and Tan, G. S. (2002) Molecular characterization of hepatitis B virus surface antigen mutants in Singapore patients with hepatocellular carcinoma and hepatitis B virus carriers negative for HBsAg but positive for anti-HBs and anti-HBc. J Gastroenterol Hepatol 17 SupplS491-496