2020-12-18T17:31:32+08:002020-03-06|Publish|

Monograph

  1. Zhang XD, 2011. Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-scale RNAi Research. Cambridge University Press, Cambridge, UK (ISBN: 9780521734448 or 9780521517713, amazon.com).

Articles in peer-reviewed journals

  1. Zhang XD*#, Wang D#, Sun S, Zhang H*. 2020. Issues of z-factor and an approach to avoid them for quality control in high-throughput screening studies. Bioinformatics (Accepted)
    + 5yr IF 9.853
    + Rank 1 in original research in Computational Mathematics by Scimago, Rank 3 in Mathematical & Computational Biology, Rank 5 in Statistics and Probability
  2. Huang C#, Zhu B#, Leng D, Ge W*, Zhang XD*. 2020. The lncRNAs Implicated in RedoxEDOX Regulation in Ybx1 Deficient Zebrafish Larvae. FEBS Open Bio (Accepted)
  3. Xue M#, Zeng Y#, Qu H# , Zhang T, Li N, Huang H, Zheng P, Hu H, Zhou L, Duan Z, Zhang Y, Bao W, Tian L, Hakonarson H, Nanshan Zhong*, Zhang XD*, Sun B*. 2020. Heparin- binding protein levels correlated with aggravation and multi-organ damage in severe COVID-
  4. ERJ Open Research (In press) (DOI: https://doi.org/10.1183/23120541.00741-2020)
  5. Lei KC, Zhang XD*. 2020. Conservation analysis of SARS-CoV-2 spike suggests complicated viral adaptation history from bat to human. Evolution, Medicine and Public Health (In press) (DOI: https://doi.org/10.1093/emph/eoaa041)
  6. Luo W#, Wang D#, Zhang T, Zheng P, Leng D, Li L, Liu Y, Sun B*, Zhang XD*. 2020. Prevalence patterns of allergen sensitization by region, gender, age and season among patients with allergic symptoms in mainland China: A four-year multicenter study. Allergy (in press) (DOI: https://doi.org/10.1111/all.14597)
    + Rank 2 in allergy by Clarivate Analytics
    + 2019IF 8.706
  7. Zheng P#, Huang C#, Dongliang Leng, Sun B*, Zhang XD*. 2020. Transcriptome analysis of peripheral whole blood identifies crucial lncRNAs implicated in childhood asthma. BMC Medical Genomics 13 (1): 136 (doi: https://doi.org/10.1186/s12920-020-00785-y)
  8. Xue M#, Zhang T#, Hu H, Huang Z, Zhen Y, Liang Y, Zhang XD*, Sun B*. 2020. Predictive effects of IgA and IgG combination to assess pulmonary exudation progression in COVID-19 patients. Journal of Medical Virology (doi: https://doi.org/10.1002/jmv.26437)
  9. Zhang W, Xie R, Zhang XD, Lee LTO, Zhang H, Yang M, Peng B, Zheng J*. 2020. Organism dual RNA‐seq reveals the importance of BarA/UvrY in Vibrio parahaemolyticus virulence. The FASEB Journal (in press) (doi: https://doi.org/10.1096/fj.201902630R)
  10. Chen C#, Sun S#, Cao Z, Shi Y, Sun B, Zhang XD*. 2019. Comparison of R packages for calculating sample entropy. Biology Methods & Protocols 4(1): bpz016 (doi: 1093/biomethods/bpz016)
  11. Leng D#, Huang C#, Lei KC, Sun S, Sun B, Zhang XD*. 2019. Co-expression network analysis of lncRNAs and mRNAs in Rats liver tissue reveals the complex interactions in response to pathogenic cytotoxicity. International Journal of Biological Sciences 15: 2296- 2307 (doi: 7150/ijbs.33735)
  12. Chen X#, Wang D#, Lin J, Zhang T, Deng S, Huang L, Jin Y, Chen C, Zhang Z, Zheng J, Sun B, Bogdan P, Zhang XD*. 2019. Analyzing complexity and fractality of glucose dynamics in a pregnant woman with type 2 diabetes under treatment. International Journal of Biological Sciences 15(11): 2373-2380 (doi:10.7150/ijbs.33825).
  13. Wu G#, Meng X#, Zheng P, Zhang XD, Li L, Hu H, Sun B*. 2019. Elevated serum levels of periostin in patients with Allergic Bronchopulmonary Aspergillosis. Mycoses 62(9):780-789 (doi: 1111/myc.12957)
  14. Huang C#, Leng D#, Lei KC, Sun S, Zhang XD*. 2019. Transcriptome analysis reveals lncRNA-mediated complex regulatory network response to DNA damage in the liver tissue of Rattus norvegicus. Journal of Cellular Physiology 234:23216–23231 (doi:10.1002/jcp.28889).
  15. Sun X, Liu X, Xia M, Shao Y, Zhang XD*. 2019. Multicellular gene network analysis identifies a macrophage-related gene signature predictive of therapeutic response and prognosis of gliomas. Journal of Translational Medicine 17 (1), 159 (doi: 10.1186/s12967-019-1908-1)
  16. Dong X#, Chen C#, Geng Q, Cao Z, Chen X, Lin J, Yu J, Zhang Z, Shi Y, Zhang XD*. 2019 An improved method of handling missing values in the analysis of sample entropy for continuous monitoring of physiological signals. Entropy 21(3), 274 (doi: 3390/e21030274)
  17. Chen X#, Guan W#, Sun S, Zheng P, Sun L, Chen D, Wang D, Chen C, Sun B*, Zhang XD*. 2019. Effects of intranasal cellulose powder on asthma control in children with mild-to- moderate persistent allergic rhinitis: A single-center, randomized, placebo-controlled trial. American Journal of Rhinology & Allergy 33 (2), 184-193
  18. Huang C, Leng D, Sun S, Zhang XD*. 2019. Re-analysis of the coral Acropora digitifera transcriptome reveals the a complex lncRNAs-mRNAs interaction network implicated in response of transcript repertoire to Symbiodinium infection. BMC Genomics 20:48 (doi: 1186/s12864-019-5429-3)
  19. Shi Y*, Li Y, Cai M, Zhang XD. 2019. A lung sound category recognition method based on wavelet decomposition and BP neural network. International Journal of Biological Sciences 15(1): 195-207. (doi: 10.7150/ijbs.29863)
  20. Wang YY#, Jin Y#, Chen C#, Zheng W#, Wang SB#, Ungvari GS, Ng CH, Zhang XD, Xiang YT*. 2019. Meta-analysis of adherence to highly active antiretroviral therapy in patients with HIV infection in China. AIDS Care 31:8, 913-922 (doi: 10.1080/09540121.2018.1554238)
  21. Wang Y, Shan Y, Gao X, Gong R, Zheng J, Zhang XD, Zhao Q. 2018. Screening and expressing HIV-1 specific antibody fragments in Saccharomyces cerevisiae. Molecular Immunology 103:279-285.
  22. Zou J, Zhang W, Zhang H, Zhang XD, Peng B, Zheng J. 2018. Studies on Aminoglycoside Susceptibility Identified a Novel Function of KsgA to Secure Translational Fidelity during Antibiotic Stress. Antimicrobial Agents and Chemotherapy 62 (10), e00853-18.
  23. Xue M#, Wang D#, Zhang Z, Cao Z*, Luo Z, Zheng Y, Lu J, Zhao Q, Zhang XD*. 2018. Demonstrating the Potential of Using Transcutaneous Oxygen and Carbon Dioxide Tensions to Assess the Risk of Pressure Injuries. International Journal of Biological Sciences 14(11):1466-1471 (doi:10.7150/ijbs.26987)
  24. Sun S#, Jin Y#, Chen C, Sun B, Cao Z, Lo LL, Zhao Q, Zheng J, Shi Y*, Zhang XD*. 2018. Entropy Change of Biological Dynamics in Asthmatic Patients and Its Diagnostic Value in Individualized Treatment: A Systematic Review. Entropy 20 (6), 402 (doi:10.3390/e20060402)
  25. Chen Z#, Liu J#, Chu D#, Shan Y, Ma G, Zhang H, Zhang XD, Wang P, Chen Q, Deng C, Chen W, Dimitrov DS, Zhao Q*. 2018. A dual-specific IGF-I/II human engineered antibody domain inhibits IGF signaling in breast cancer cells. International Journal of Biological Sciences 14(7): 799-806 (doi: 10.7150/ijbs.25928)
  26. Ren S, Shi Y*, Cai M, Zhao H*, Zhang Z, Zhang XD. 2018. ANSYS-MATLAB co-simulation of mucus flow distribution and clearance effectiveness of a new simulated cough device. International Journal for Numerical Methods in Biomedical Engineering: e2978 (DOI: 1002/cnm.2978)
  27. Xie R, Zhang XD, Zhao Q, Peng B, Zheng J*. 2018. Analysis of global prevalence of antibiotic resistance in acinetobacter baumannii infections disclosed a faster increase in OECD countries. Emerging Microbes & Infections 7:31. (DOI 10.1038/s41426-018-0038-9)
  28. Shi Y#, Wang G#, Niu J*, Zhang Q, Cai M, Sun B, Wang D, Xue M, Zhang XD*. 2018. Classification of sputum sounds using artificial neural network and wavelet transform. International Journal of Biological Sciences 14(8): 938-945 (DOI: 10.7150/ijbs.23855)
  29. Zhang XD#*, Zhang Z#, Wang D. 2018. CGManalyzer: an R package for analyzing continuous glucose monitoring studies. Bioinformatics 34(9): 1609–1611 (DOI: 1093/bioinformatics/btx826)
    + 5yr IF 9.853
    + Rank 1 in Computational Mathematics by Scimago, Rank 3 in Mathematical & Computational Biology, Rank 5 in Statistics and Probability
  30. Ren S, Cai M, Shi Y*, Xu W, Zhang XD*, 2018. Influence of bronchial diameter change on the airflow dynamics based on a pressure-controlled ventilation system. International Journal for Numerical Methods in Biomedical Engineering: e2929 (doi: 10.1002/cnm.2929)
  31. Niu J#, Shi Y#*, Cai M, Cao Z, Wang D, Zhang Z, Zhang XD*. 2017. Detection of sputum by interpreting the time-frequency distribution of respiratory sound signal using image processing techniques. Bioinformatics 34(5): 820-827 (DOI: 10.1093/bioinformatics/btx652)
    + 5yr IF 9.853
    + Rank 1 in Computational Mathematics by Scimago, Rank 3 in Mathematical & Computational Biology, Rank 5 in Statistics and Probability
  32. Wang Y#, Liu H#, Leng D, Gao W*, Cai M, Xu W, Zhang XD, Shi Y*. 2017. New advances in EMG control of anthropomorphic prosthetic hand. Science China Technological Sciences (DOI: 10.1007/s11431-017-9159-3)
  33. Xu T, Ying T, Wang L, Zhang XD, Kang L, Huang T, Cheng L, Wang L*, Zhao Q*. 2017. A native-like bispecific antibody suppresses the inflammatory cytokine response by simultaneously neutralizing tumor necrosis factor-alpha and interleukin-17. Oncotarget 8(47): 81860–81872. (doi: 18632/oncotarget.19899)
  34. Jin Y#, Chen C#, Cao Z, Sun B, Lo IL, Liu TM, Zheng J, Sun S, Shi Y*, Zhang XD*. 2017. Entropy change of biological dynamics in human chronic obstructive pulmonary disease. International Journal of Chronic Obstructive Pulmonary Diseases 12: 2997–3005 (doi: 2147/COPD.S140636)
  35. Chen C#, Jin Y#, Lo IL, Zhao H, Sun B, Zhao Q, Zheng J, Zhang XD*. 2017. Complexity Change in Cardiovascular Diseases. International Journal of Biological Sciences 13(10): 1320-1328 (doi: 10.7150/ijbs.19462)
  36. Zhang XD#, Pechter D#, Yang L, Ping X, Yao Z, Zhang R, Shen X, Li N, Connick J, Hill D, Nawrocki AR, Li C*. 2017. Decreased complexity of glucose dynamics preceding the onset of diabetes in preclinical species. PloS ONE 12(9):e0182810 .(dio:10.1371/journal.pone.0182810)
  37. Shi Y*, Zhang B, Cai M, Zhang XD*. 2017. Numerical Simulation of volume-controlled mechanical ventilated respiratory system with two different lungs. International Journal for Numerical Methods in Biomedical Engineering 33 (9): e2852 (doi: 10.1002/cnm.2852).
  38. He L, Liu S, Shan C, Tu Y, Li Z, Zhang XD*. 2016. Demonstrating placebo effect in clinical trials of DPP-4 inhibiters conducted in China: Meta-analysis. BMC Pharmacology and Toxicology 17:40 (doi: 10.1186/s40360-016-0084-7)
  39. Cox KS, Wang IM, Nefedov A, Zhang XD, Dubey S, Bett A, Casimiro D, Mandl J, Feinberg MB. 2016. Comparison of the TLR7 and TLR9 innate immune signaling pathways in african green monkeys and rhesus macaques. Journal of Immunology 196 (1 Supplement) 203.8
  40. Zhao G, Li Q, Wang IM, Li X, Fang X, Zhang XD*. 2015. An effective analytic method for detecting tissue-specific genes from RNA-seq data. Pharmacogenomics 16 (16):1769-1779 (doi: 10.2217/pgs.15.118).
  41. Zhang XD*. 2015. Precision medicine, personalized medicine, omics and Big Data: concepts and relationships. Journal of Pharmacogenomics and Pharmacoproteomics 6:2 (doi: 10.4172/2153-0645.1000e144).
  42. Kang H, Cho KH, Zhang XD, Zeng T*, Chen L*. 2015. Inferring sequential order of somatic mutations during tumorgenesis based on markov chain model. IEEE/ACM Transactions on Computational Biology and Bioinformatics 99 (1109/TCBB.2015.2424408)
  43. Camargo LM, Zhang XD, Loerch P, Caceres M, Marine SD, Uva P, Ferrer M, Rinaldis E, Stone DJ, Majercak J, Ray WJ, Chen Y, Shearman MS, Mizuguchi K. 2015. Pathway-based analysis of genome-wide siRNA screens reveals the regulatory landscape of APP processing PLoS ONE 10(2): e0115369. (doi:10.1371/journal.pone.0115369)
  44. Gould AL*, Zhang XD. 2014. Bayesian adaptive determination of the sample size required to assure acceptably low adverse event risk. Statistics in Medicine 33(6): 940-957 (DOI: 10.1002/sim5993)
  45. Zhang XD*, Zhang Z. 2013. displayHTS: a R package for displaying data and results from high-throughput screening experiments. Bioinformatics 29 (6): 794–796 (doi: 1093/bioinformatics/btt060).
    + 5yr IF 9.853
    + Rank 1 in Computational Mathematics by Scimago, Rank 3 in Mathematical & Computational Biology, Rank 5 in Statistics and Probability
  46. Yang R*, Lacson RG, Castriota G, Zhang XD, Liu Y, Zhao WQ, Einstein M; Camargo, Luiz CM, Qureshi S, Wong KK, Zhang BB, Ferrer M, Berger JP. 2012. A genome-wide siRNA screen to identify modulators of insulin sensitivity and gluconeogenesis. PLoS ONE 7(5): e36384. (doi:10.1371/journal.pone.0036384)
  47. Zhang XD*, Heyse JF. 2012. Contrast variable for comparing groups in biopharmaceutical research. Statistics in Biopharmaceutical Research 4 (3): 228 – 239 (DOI: 1080/19466315.2011.646905).
  48. Zhang XD*, Santini F, Lacson R, Marine SD, Wu Q, Benetti L, Yang R, McCampbell A, Berger JP, Toolan DM, Stec EM, Holder DJ, Soper KA, Heyse JF and Ferrer M. 2011. cSSMD: Assessing collective activity of multiple siRNAs in genome-scale RNAi screens. Bioinformatics 27(20): 2775-2781 (doi: 10.1093/bioinformatics/BTR474)
    +listed among the 50 most-frequently cited articles in Bioinformatics in 2013
    + 5yr IF 9.853
    + Rank 1 in Computational Mathematics by Scimago, Rank 3 in Mathematical & Computational Biology, Rank 5 in Statistics and Probability
  49. Zhang XD*. 2011. Illustration of SSMD, z-score, SSMD*, z*-score and t-statistic for hit selection in high-throughput screens. Journal of Biomolecular Screening 16 (7): 775 – 785 (doi: 10.1177/1087057111405851).
    +listed among the 50 most-frequently cited articles in Journal of Biomolecular Screening since 2014
  50. Zhang XD*, 2010. Contrast variable potentially providing a consistent interpretation to effect sizes. Journal of Biometrics & Biostatistics 1:108 (doi:10.4172/2155-6180.1000108).
  51. Zhang XD*, Lacson R, Yang R, Marine SD, McCampbell, Toolan DM, Hare TR, Kajdas J, Berger JP, Holder DJ, Heyse JF, Ferrer M. 2010. The use of SSMD-based false discovery and false non-discovery rates in genome-scale RNAi screens. Journal of Biomolecular Screening 15: 1123 – 1131 (doi: 10.1177/1087057110381919).
  52. Zhang XD*, 2010. An effective method controlling false discoveries and false non-discoveries in genome-scale RNAi screens. Journal of Biomolecular Screening 15: 1116 – 1122 (doi: 1177/1087057110381783).
  53. Zhao WQ, Santini F, Breese R, Ross D, Zhang XD, Stone DJ, Ferrer M, Townsend M, Wolfe AL, Seager MA, Kinney GG, Shughrue PJ, Ray WJ. 2010. Inhibition of calcineurin-mediated endocytosis and AMPA receptor prevent amyloid β oligomer-induced synaptic disruption. Journal of Biological Chemistry 285(10): 7619-7632 (doi:1074/jbc.M109.057182).
  54. Zhang XD*. 2010. Assessing the size of gene or RNAi effects in multi-factor high-throughput experiments. Pharmacogenomics 11(2): 199 – 213 (doi:10.2217/PGS.09.136)
  55. Zhang XD*. 2010. Strictly standardized mean difference, standardized mean difference and classical t-test for the comparison of two groups. Statistics in Biopharmaceutical Research 2(2): 292-299 (doi: 1198/sbr.2009.0074)
  56. Klinghoffer RA, Frazier J, Annis J, Berndt JD, Roberts BS, Arthur WT, Lacson R, Zhang XD, Ferrer M, Moon, RT, Cleary MA. 2009. A lentivirus-mediated genetic screen identifies dihydrofolaste reductase (DHFR) as a modulator of  -actenin/GSK3 signaling. PLoS ONE 4(9): e6892 (doi: 1371/journal.pone.0006892)
  57. Zhang XD*, Heyse JF. 2009. Determination of sample size for hit selection in genome-scale RNAi screens. Bioinformatics 25: 841-844 (doi:1093/bioinformatics/btp082)
    + 5yr IF 9.853
    + Rank 1 in Computational Mathematics by Scimago, Rank 3 in Mathematical & Computational Biology, Rank 5 in Statistics and Probability
  58. Zhang XD*, Shane SD, Ferrer M. 2009. Error rates and power in genome-scale RNAi screens. Journal of Biomolecular Screening 14:230-238 (doi:1177/1087057109331475)
  59. Zhang XD*. 2009. A method effectively comparing gene effects in multiple conditions in RNAi and expression profiling research. Pharmacogenomics 10(3):345-358 (doi:10.2217/14622416.10.3.345)
  60. Zhou H, Xu M, Huang Q, Gates AT, Zhang XD, Stec EM, Ferrer M, Hazuda DJ, Espeseth AS. 2008. Genome-scale RNAi screen for host factors required for HIV replication. Cell Host & Microbe 4(5):495-504 (doi:1016/j.chom.2008.10.004).
    +listed by Nature Medicine in its year end review on Notable advances in 2008 (http://www.nature.com/nm/journal/v14/n12/full/nm1208-1302.html)
    +selected to appear in the cover page of the November issue of Cell Host & Microbe
    + 5yr IF 17.766
  61. Zhang XD*, Kuan PF, Ferrer M, Shu X, Liu YC, Gates AT, Kunapuli P, Stec EM, Xu M, Marine SD, Holder DJ, Stulovici B, Heyse JF, Espeseth AS. 2008. Hit selection with false discovery rate control in genome-scale RNAi screens. Nucleic Acids Research 36 (14):4667- 4679 (doi:1093/nar/gkn435).
    + 5yr IF 11.797
  62. Zhang XD*. 2008. Genome-wide screens for effective siRNAs through assessing the size of siRNA effects. BMC Research Notes 1:33 (doi:1186/1756-0500-1-33).
  63. Zhao WQ, Breese R, Wolfe AA, Ross DA, Santini F, Zhang XD, Ferrer M, Stone D, Seabrook GR, Stulovici B, Kinney GG, Ray WJ, Shughrue PJ. 2008. Targeting synaptic AMPA receptors by A Alzheimers & Dementia 4 (4):T197 (doi: http://dx.doi.org/10.1016/j.jalz.2008.05.548).
  64. Zhang XD*, Espeseth AS, Johnson E, Chin J, Gates A, Mitnaul L, Marine SD, Tian J, Stec EM, Kunapuli P, Holder DJ, Heyse JF, Stulovici B, Ferrer M. 2008. Integrating experimental and analytic approaches to improve data quality in genome-wide RNAi screens. Journal of Biomolecular Screening 13(5): 378-389 (doi: 1177/1087057108317145).
    +selected to appear in the cover page of the June issue
  65. Zhang XD*, 2008. Novel analytic criteria and effective plate designs for quality control in genome-wide RNAi screens. Journal of Biomolecular Screening 13(5): 363-377 (doi:1177/1087057108317062)
    +listed among the 50 most-frequently cited articles in Journal of Biomolecular Screening since 2013
    (http://jbx.sagepub.com/reports/most-cited)
  66. Chung N, Zhang XD, Kreamer A, Locco L, Kuan PF, Bartz S, Linsley PS, Ferrer M, Strulovici B. 2008. Median absolute deviation to improve hit selection for genome-scale RNAi screens. Journal of Biomolecular Screening 13: 149-158 (doi: 1177/1087057107312035).
    +listed among the 50 most-frequently cited articles in Journal of Biomolecular Screening since 2011
  67. Clodfelter KH, Miles GD, Wauthier V, Holloway MG, Zhang XD, Hodor P, Ray WJ, Waxman DJ. 2007. Role of STAT5a in Regulation of Sex-specific Gene Expression in Female but not Male Mouse Liver Revealed by Microarray Analysis. Physiological Genomics 31:63-74 (PMID: 17536022).
  68. Zhang XD*. 2007. A new method with flexible and balanced control of false negatives and false positives for hit selection in RNA interference high throughput screening assays. Journal of Biomolecular Screening 12 (5): 645-655 (doi:10.1177/1087057107300645)
    +listed among the 50 most-frequently cited articles in Journal of Biomolecular Screening since April 2009
  69. Zhang XD*, Ferrer M, Espeseth AS, Marine SD, Stec EM, Crackower MA, Holder DJ, Heyse JF, Strulovici B. 2007. The use of strictly standardized mean difference for hit selection in primary RNA interference high throughput screening experiments. Journal of Biomolecular Screening 12 (4): 497-509 (doi:1177/1087057107300646).
    +listed among the 50 most-frequently cited articles in Journal of Biomolecular Screening since 2008
  70. Zhang XD*. 2007. A pair of new statistical parameters for quality control in RNA interference high throughput screening assays. Genomics 39: 552-561 (doi: 1016/j.ygeno.2006.12.014).
  71. Kim JJ, Shirts BH, Dayal M, Bacanu S, Wood J, Xie W, Zhang X, Chowdari KV, Yolken R, Devlin B, Nimgaonkar VL. 2007. “Are exposure to cytomegalovirus and genetic variation on chromosome 6p as joint risk factors for schizophrenia?” Annals of Medicine 39(2):145-53 (doi: 10.1080/07853890601083808).
  72. Espeseth AS, Huang Q, Gates AT, Xu M, Yu Y, Simon AJ, Shi X, Zhang XD, Hodor PG, Stone D, Burchard J, Cavet GL, Bartz S, Linsley PS, Ray WJ, Hazuda DJ. 2006. A genome wide analysis of ubiquitin ligases in APP processing identifies a novel regulator of BACE1 mRNA levels. Molecular and Cellular Neuroscience 33(3): 227-235.
  73. Zhang XD*, Yang XC, Chung N, Gates AT, Stec EM, Kunapuli P, Holder DJ, Ferrer M, Espeseth AS. 2006. Robust statistical methods for hit selection in RNA interference high throughput screening experiments. Pharmacogenomics 7 (3) 299-309 (doi: 2217/14622416.7.3.299).
  74. Johnson TE, Zhang X, Shu S, Umbenhauer DR. 2005. Statins and PPAR  agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co- treatment. Toxicology and Applied Pharmacology 208 (3) 210-221 (PMID: 16239165).
  75. Roeder K, Bacanu S, Sonpar V, Zhang X, Devlin B. 2005. Analysis of Single-Locus Tests to Detect Gene/Disease Associations. Genetic Epidemiology 28 (3) 207-219 (PMID: 15637715)
  76. Johnson TE, Zhang X, Bleicher KB, Dysart G, Loughlin AF, Schaefer WH, Umbenhauer DR. 2004. Statins induce apoptosis in rat and human myotube cultures by inhibiting protein geranylgeranylation but not ubiquinone. Toxicology and Applied Pharmacology 200 (3): 237- 250 (PMID: 15504460).
  77. Parrish ML, Wei N, Duenwald S, Tokiwa GY, Wang Y, Holder DJ, Dai H, Zhang X, Wright C, Hodor P, Cavet G, Phillips R, Sun BI, Fare TL. 2004. A microarray platform comparison for neuroscience applications. Journal of Neuroscience Methods 132: 57-68 (PMID: 14687675).
  78. Zhang X, Roeder K*, Wallstrom G, Devlin B. 2003. Integration of association statistics over genomic regions using Bayesian adaptive regression splines. Human Genomics 1: 20-29 (doi:1186/1479-7364-1-1-20; PMID: 15601530 link).
  79. Mao SX and Zhang X. 1999. Gene diversity, gene differentiation coefficients of parent populations and prediction of their F1 heterosis. Journal of Biomathematics 14: 7-11

Editorial Articles

  1. Yongzhao Shao, Wei Pan, Zhang XD. 2012. Advanced designs and statistical methods for genetic and genomic studies of complex diseases. Journal of Probability and Statistics e805426 (doi: 10.1155/2012/805426)

Articles in Peer-Reviewed Proceedings

  1. Lei K, Zhang XD*. 2018. An approach on discretizing time series using recurrent neural network. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2522 – 2526. (IEEE Catalog Number: CFP18BIB-USB; ISBN: 978-1-5386- 5487-3)
  2. Dong X#, Chen C#, Cao Z, Geng Q, Jin Y, Shi Y, Zhang XD*. 2018. An improved method for using sample entropy to reveal medical information in data from continuously monitored physiological signals. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2502 – 2506.
  3. Huang C, Leng D, Li L, Zheng P, Sun B*, Zhang XD*. 2018. Transcriptome analysis of human peripheral blood reveals key circRNAs implicated in allergic bronchopulmonary aspergillosis. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2507 – 2514.
  4. Jin Y, Zhang T, Cao Z, Zhao N, Chen C, Wang D, Lei K, Leng D, Zhang XD*. 2018. Prediction indicators for acute exacerbations of chronic obstructive pulmonary disease by combining non-linear analyses and machine learning. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2515 – 2521.
  5. Leng D#, Huang C#, Lei K, Sun S, Zhang XD*. 2018. Exploration of dysregulated lncRNA- mRNA network from the RNA-seq data of rats induced by three different synthetic cytotoxic compounds. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2527 – 2534.
  6. Sun S, Chen C, Huang C, Zhang XD*.2018. Application of arrayed CRISPR/Cas9 screen and its data analysis: a systematic review. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2549 – 2555.
  7. Wang D#, Zheng P#, Teng Zhang, Cheng Li, Lichun Chen, Yingying Zhai, Dongliang Leng, Yu Jin, Sun B*, Zhang XD*. 2018. Analysis of the complexity patterns in respiratory data. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2556 – 2560.
  8. Zhang T#, Jin Y#, Sun S, Liu Y, Zhang XD*. 2018. Analysis of impact factors of multiscale entropy. Proceedings of 2018 IEEE International Conference on Bioinformatics and Biomedicine: 2568 – 2572.
  9. Zhang XD, Wang D, Zhao H. 2016. Thoughts on informatization and atandardization of the diagnosis in traditional Chinese medicine. Proceedings of the 13th World Congress of Traditional Chinese Medicine.
  10. Wenxian Huang, Zhang XD, Yong Li, William W Wang, Keith Soper. 2012. Standardized median difference for quality control in high-throughput screening. Proceedings of 2012 International Symposium on Information Technologies in Medicine and Education (ITME): 515 – 518.
  11. Zhang XD*. 2007. Threshold determination of strictly standardized mean difference in RNA interference high throughput screening assays. IMECS Proceeding: 261-266
  12. Zhang XD*, Espeseth AS, Chung N, Ferrer M. 2006. Evaluation of a novel metric for quality control in an RNA interference high throughput screening assay. BIOCOMP:385-390.

Articles in Non-Peer-Reviewed Conference Proceedings

  1. Wang D, Zhang Z, Zhang XD*. 2019. Continuous glucose monitoring technology and a workflow for its data analysis. The 2019 American Statistical Association Proceedings, Alexandria, VA: American Statistical Association: 3164-3172.
  2. Zhang XD*. 2018. Digital medicine for diabetes. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 360-361.
  3. Jin Y, Zhang XD*. 2018. Prediction model for acute exacerbation of chronic obstructive pulmonary disease using psychological signals from home ventilators: a systematic review. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 363.
  4. Chen X,#, Wang D#, Lin J, Jin Y, Zhang T, Deng S, Huang L, Chen C, Zhang Z, Zheng J, Bogdan P, Zhang XD*. 2018. Demonstrating an effective method integrating CSII, CGM and complexity analysis to treat a pregnant woman with type II diabetes. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 362.
  5. Leng D, Huang C, Lei J, Sun S, Zhang XD*. 2018. Exploration of dysregulated lncRNA- mRNA network from the RNA-seq data of rat depends on cytotoxin chemical treatment. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 50.
  6. Huang C, Leng D, Zhang XD*. 2018. Transcriptome analysis reveals specific circRNAs implicated in two respiratory disease: ABPA and asthma. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 346.
  7. Deng M, Zhang XD*. 2018. Empirical likelihood test for the product of means. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 133.
  8. Zhang T, Zhang XD*. 2018. Analysis of Impact factors of multiscale entropy by numerical simulation. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 132.
  9. Dong X#, Chen C#, Geng Q, Cao Z, Jin Y, Shi Y, Zhang XD*. 2018. A method of handling missing values in the analysis of sample entropy for continuous monitoring of physiological signals. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 118.
  10. Sun S, Zhang XD*. 2018. Review of arrayed screens based on CRISPR/cas9 technology. Proceedings of the 8th National Conference on Bioinformatics and Systems Biology of China and the 1st (Macao) International Bioinformatics Symposium: 212.
  11. Zhang XD*. 2013. A univariate statistical parameter for assessing effect size in multivariate settings for the comparison of two groups. Proceedings of the 59th ISI World Statistics Congress, Hong Kong: International Statistical Institute: 3062 – 3066.
  12. Zhang XD*. 2010. A statistical method assessing collective activity of multiple siRNAs targeting a gene in RNAi screens. The 2010 American Statistical Association Proceedings [CD-ROM], Alexandria, VA: American Statistical Association: 3267-3281.
  13. Zhang XD*. 2007. New concept of contrast in statistical analysis. The 2007 American Statistical Association Proceedings [CD-ROM], Alexandria, VA: American Statistical Association: 637-648.
  14. Zhang XD*, Espeseth AS, Chung N, Holder DJ, Ferrer M. 2006. The use of strictly standardized mean difference for quality control in RNA interference high throughput screening experiments. The 2006 American Statistical Association Proceedings, Alexandria, VA: American Statistical Association: 882-886.
  15. Zhang X*, Yang XC, Chung N, Gates AT, Stec E, Kunapuli P, Holder D, Ferrer M, Espeseth AS. 2005. Exploring statistical methods for hit selection in RNA interference high throughput screening experiments. The 2005 American Statistical Association Proceedings, Alexandria, VA: American Statistical Association: 775-780.
  16. Shu XH, Zhang X, Li J, Wei N, Sun B. 2005. Power comparison of statistical methods for detecting differential expression in microarray experiments. The 2005 American Statistical Association Proceedings, Alexandria, VA: American Statistical Association: 723-729.
  17. Zhang X*, Amaratunga D, Roeder K. 2003. Identifying important genes using differential expression and classification error. The 2003 American Statistical Association Proceedings, Alexandria, VA: American Statistical Association: 4751-4758.

Book Chapters

  1. Zhang XD*. 2017. Entropy for the complexity of physiological signal dynamics. In Shen B. editor, Healthcare and Big Data Management Springer Nature Singapore.39-53. (DOI: 1007/978-981-10-6041-0_3)
  2. He P, Wu Z, Zhang XD*, Geng Z. 2016. Identification of Causal Mediation Models with an Unobserved Pretreatment Confounder.In He H, Wu P and Chen D editors, Statistical Causal Inferences and Their Applications in Public Health Research. Springer International Publishing, Switzerland.241-262.

Articles in Peer-Reviewed Chinese Journals

  1. Zhang X, Wang XY, Shu XH. 2003. DNA microarrays and data analysis. In Ma Y and Wang J. editors, The Principle and Technique of Neuroscience, Chongqing Publish House, Chongqing, China, 324-335
  2. Wang XY, Zhang X. 2003. DNA microarrays and their application in neuroscience. In Ma Y and Wang J. editors, The Principle and Technique of Neuroscience, Chongqing Publish House, Chongqing, China, 336-346
  3. Zhang X, Zhang YX, Xiong CX. 1993. Breeding studies of Colossoma brachypomum in ponds. Nanchang Fisheries 51: 3-8
  4. Zhang YX, Zhang X, Qian XK, Xiong CX. 1993. Survival studies and disease prevention of Colossoma brachypomum through winter. Nanchang Fisheries 51: 9-13
  5. Xiong CX, Zhang YX, Zhang X. 1993. Breeding experiment of Colossoma brachypomum in high density. Nanchang Fisheries 52: 5-7
  6. Xiong CX, Zhang YX, Zhang X. 1992. Breeding experiment of Carp. Nanchang Fisheries 50: 10-11
  7. Xiong CX, Zhang YX, Liu JZ, Tu PW, Huang H, Zhang X. 1992. Survival experiment of Colossoma brachypomum through winter in well water. Nanchang Fisheries 50: 12-14.
  8. Zhang X, Liu JZ, Chen DC, Li SQ, Xu LQ, Xiong CX, Qian XQ, Wang JL. 1992. Survival studies of Colossoma brachypomum through winter in spring water. Nanchang Fisheries 50: 16-19

*: corresponding author

#: co-first authors