2024-04-08T14:51:16+08:002022-09-09|
聯絡信息
職稱
研究助理教授
辦公室
(辦公室)E12-1023
電郵
beili@um.edu.mo
諮詢時間

星期三、五 16:00-17:00

教學
Education
PhD The University of Queensland, Australia (2019)
MMS Beijing University of Chemical Technology, China (2015)
BSc Beijing University of Chemical Technology, China (2011)
Position
07/2022 – Present Research Assistant Professor, Faculty of Health Sciences, University of Macau
07/2020 – 07/2022 Postdoctoral Fellow, Faculty of Health Sciences, University of Macau
09/2019 – 02/2020 Research Assistant, Australian Institute for Bioengineering and Nanotechnology, The University of Queensland
Research Interests
Precision cancer immunotherapy, Bioresponsive materials, Immunoadjuvants, Targeted drug delivery system, Reprogramming of tumor-associated immunosuppression, Postsurgical tumor inhibition, Tumor-derived exosome, Programmed cell death, Imaging-guided cancer treatment.

 

Representative Publications
  1. Bei Li, Zi Gu*, Nyoman Kurniawan, Weiyu Chen, Zhi Ping Xu*, Manganese-based layered double hydroxide nanoparticles as a T1-MRI contrast agent with ultrasensitive pH response and high relaxivity. Advanced Materials 2017, 29, 1700373.
  2. Bei Li, Guanyu Hao, Bing Sun, Zi Gu*, Zhi Ping Xu*, Engineering a therapy-induced “immunogenic cancer cell death” amplifier to boost systemic tumor elimination. Advanced Functional Materials 2020, 30, 1909745.
  3. Guohao Wang#, Lisi Xie#, Bei Li# (Co-first author), Wei Sang, Jie Yan, Jie Li, Hao Tian, Wenxi Li, Zhan Zhang, Ye Tian, Yunlu Dai*, A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis. Nature Communications 2021, 12, 5733.
  4. Jie Li#, Lisi Xie#, Bei Li# (Co-first author), Chao Yin, Guohao Wang, Wei Sang, Wenxi Li, Hao Tian, Zhan Zhang, Xuanjun Zhang, Quli Fan*, Yunlu Dai*, Engineering a hydrogen sulfide-based nanomodulator to normalize hyperactive photothermal immunogenicity for combination cancer therapy. Advanced Materials 2021, 33, 2008481.
  5. Bei Li, Jie Tang, Weiyu Chen, Guanyu Hao, Nyoman Kurniawan, Zi Gu*, Zhi Ping Xu*, Novel theranostic nanoplatform for complete mice tumor elimination via MR imaging-guided acid-enhanced photothermo-/chemo-therapy. Biomaterials 2018, 177, 40.
  6. Jie Yan#, Bei Li# (Co-first author), Piaoping Yang*, Jun Lin*, Yunlu Dai*, Progress in light-responsive lanthanide nanoparticles toward deep tumor theranostics. Advanced Functional Materials 2021, 31, 2104325.
  7. Bei Li, Yufei Zhao, Shitong Zhang, Wa Gao, Min Wei*, Visible-light-responsive photocatalysts toward water oxidation based on NiTi-layered double hydroxide/reduced graphene oxide composite materials. ACS Applied Materials & Interfaces, 2013, 5, 10233.
  8. Jiaxin Li#, Bei Li# (Co-first author), Jikang Wang, Lei He*, Yufei Zhao*, Recent advances in layered double hydroxides and their derivatives for biomedical applications. Acta Chimica Sinica 2021, 79, 238.
  9. Zhan Zhang, Bei Li, Lisi Xie, Wei Sang, Hao Tian, Jie Li, Guohao Wang, Yunlu Dai*, Metal-phenolic network-enabled lactic acid consumption reverses immunosuppressive tumor microenvironment for sonodynamic therapy. ACS Nano 2021, 15, 16934.
  10. Jie Tang, Bei Li, Christopher B. Howard, Stephen M. Mahler, Kristofer J. Thurecht, Yilun Wu, Leaf Huang, Zhi Ping Xu*, Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials 2019, 216, 119232.
  11. Zhenbang Cao, Bei Li, Luyao Sun, Zhi Ping Xu*, Zi Gu*, 2D layered double hydroxide nanoparticles: recent progress toward preclinical/clinical nanomedicine. Small Methods 2019, 4, 1900343.
  12. Yufei Zhao, Bei Li, Qiang Wang, Wa Gao, Chengle J. Wang, Min Wei*, David G. Evans, Xue Duan, Dermot O’Hare*, NiTi-layered double hydroxides nanosheets as efficient photocatalysts for oxygen evolution from water using visible light. Chemical Science 2014, 5, 951.
  13. Li Li, Bei Li, Weiyi Gu, Zhi Ping Xu*, Modifying layered double hydroxide nanoparticles for tumor imaging and therapy. Clays and Clay Minerals 2019, 67, 72.
  14. Weiyu Chen, Huali Zuo, Bei Li, Chengcheng Duan, Barbara Rolfe, Bing Zhang, Timothy J. Mahony*, Zhi Ping Xu*, Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation. Small 2018, 14, 1704465.
  15. Huali Zuo, Weiyu Chen, Bei Li, Kewei Xu, Helen Cooper, Zi Gu*, Zhi Ping Xu*, MnAl layered double hydroxide nanoparticles as a dual-functional platform for magnetic resonance imaging and siRNA delivery. Chemistry: A European Journal 2017, 23, 14299.
  16. Yufei Zhao, Shitong Zhang, Bei Li, Hong Yan, Shan He, Lei Tian, Wenying Shi, Jing Ma, Min Wei*, David G. Evans, Xue Duan, A family of visible-light responsive photocatalysts obtained by dispersing CrO6 octahedra into a hydrotalcite matrix. Chemistry: A European Journal 2011, 17, 13175.
  17. Jianping Liu, Yilun Wu, Changkui Fu, Bei Li, Li Li, Run Zhang*, Tiefeng Xu, Zhi Ping Xu*, Charge reversion simultaneously enhances tumor accumulation and cell uptake of layered double hydroxide nanohybrids for effective imaging and therapy. Small 2020, 16, 2002115.
  18. Chang Lu, Ye Tian, Hao Tian, Bei Li, Bo Peng, Jun Zheng*, Yunlu Dai*, An ultrasound activable metal-phenolic network nano-antibiotics for in vivo on-site infection therapy. Science China Materials 2022, https://doi.org/10.1007/s40843-022-2125-1.
  19. Yufei Zhao, Chengli J. Wang, Wa Gao, Bei Li, Qiang Wang, Lirong Zheng, Min Wei*, David G. Evans, Xue Duan, Dermot O’Hare*, Synthesis and antimicrobial activity of ZnTi–layered double hydroxide nanosheets. The Journal of Materials Chemistry B 2013, 1, 5988.
  20. Zhan Zhang, Wei Sang, Lisi Xie, Wenxi Li, Bei Li, Jie Li, Hao Tian, Zhen Yuan, Qi Zhao, Yunlu Dai*, Polyphenol-based nanomedicine evokes immune activation for combination cancer treatment. Angewandte Chemie International Edition 2021, 60, 1967.
  21. Wenxi Li, Lisi Xie, Yi Ju, Zhan Zhang, Bei Li, Jie Li, Wei Sang, Guohao Wang, Hao Tian, Yunlu Dai*, A “three musketeers” tactic for inclining interferon-γ as a comrade-in-arm to reinforce the synergistic-tumoricidal therapy. Nano Research 2022, 15, 3458.
  22. Jie Yan, Guohao Wang, Lisi Xie, Hao Tian, Jie Li, Bei Li, Wei Sang, Wenxi Li, Zhan Zhang, Yunlu Dai*, Engineering Radiosensitizer-Based Metal-Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy. Advanced Materials 2022, 34, 2105783.
  23. Wei Sang, Lisi Xie, Guohao Wang, Jie Li, Zhan Zhang, Bei Li, Sen Guo, Chu-Xia Deng, Yunlu Dai*, Oxygen-enriched metal-phenolic X-ray nanoprocessor for cancer radio-radiodynamic therapy in combination with checkpoint blockade immunotherapy. Advanced Science 2021, 8, 2003338.
  24. Jie Li, Wenxi Li, Lisi Xie, Wei Sang, Guohao Wang, Zhan Zhang, Bei Li, Hao Tian, Jie Yan, Ye Tian, Zhenhua Li, Quli Fan, Lin Yu, Yunlu Dai*, A metal-polyphenolic nanosystem with NIR-II fluorescence-guided combined photothermal therapy and radiotherapy. Chemical Comminications 2021, 57, 11473.
  25. Lisi Xie, Jie Li, Guohao Wang, Wei Sang, Mengze Xu, Wenxi Li, Jie Yan, Bei Li, Zhan Zhang, Qi Zhao, Zhen Yuan, Quli Fan, Yunlu Dai*, Phototheranostic metal-phenolic networks with antiexosomal PD-L1 enhanced ferroptosis for synergistic immunotherapy. Journal of the American Chemical Society 2022, 144, 787.
  26. Hao Tian, Guohao Wang, Wei Sang, Lisi Xie, Wenxi Li, Jie Yan, Ye Tian, Bei Li, Jie Li, Yunlu Dai*, Manganese-phenolic nanoadjuvant combines sonodynamic therapy with cGAS-STING activation for enhanced cancer immunotherapy. Nano Today 2022, 43, 101405.
Research Grants
2022 – 2024 Grant Principal Investigator, National Natural Science Foundation of China (NSFC), The Youth Science Fund, 300,000 RMB, Grant No. 32101069
Patents
  1. Min Wei*, Bei Li, Yufei Zhao, Xue Duan, Visible light response of NiTi-LDH/RGO composite photocatalyst and its preparation method. Chinese Patent: 201210440012.7
  2. Min Wei*, Yufei Zhao, Bei Li, Wa Gao, Xue Duan, Synthesis of NiTi-layered double hydroxide nanosheets. Chinese Patent: 201210434511.5
  3. Min Wei*, Yufei Zhao, Wa Gao, Bei Li, Visible light response of ZnTi-LDH composite photocatalyst and its preparation method. Chinese Patent: 201210434472.9
Awards
2019 Dean’s award for outstanding higher degree by research theses, The University of Queensland, Australia
2015 – 2019 International postgraduate research scholarship (IPRS, Top 1‰) and The University of Queensland centennial scholarship (UQCent), Australia
2017 Chinese government award for outstanding self-financed students abroad (Top 1‰), Australia
2017 Donald Tugby prize in nanotechnology (for best publication), The University of Queensland, Australia
2016 International and Domestic travel grant, The University of Queensland, Australia
2015 Outstanding graduate, Beijing University of Chemical Technology, China
2015 Outstanding Thesis Award, Beijing University of Chemical Technology, China
2013 National scholarship for outstanding graduate student, China
2007 – 2011 Excellent Undergraduate Scholarships, Beijing University of Chemical Technology, China