|The Generation and Function of risiRNA in Caenorhabditis elegans
|Prof. Shouhong GUANG
University of Science and Technology of China
|Date & Time
|08 Nov 2019 (Fir)
|Room G002, N22 Building (University of Macau)
|Ribosome biogenesis drives cell growth and proliferation, but mechanisms that modulate this process remain poorly understood. For a long time, small rRNA sequences have been widely treated as
non-specific degradation products and neglected as garbage sequences. Recently, Prof. GUANG’s team identified a new class of antisense ribosomal siRNAs (risiRNAs) that downregulate pre-rRNA through the nuclear RNAi pathway in C. elegans.In this talk, Prof. GUANG will show the generation, function, and mechanism of this new class of small interfering RNAs.