Talk title | The Generation and Function of risiRNA in Caenorhabditis elegans |
Speaker | Prof. Shouhong GUANG Professor University of Science and Technology of China |
Date & Time | 08 Nov 2019 (Fir) 15:30-16:30 |
Venue | Room G002, N22 Building (University of Macau) |
Abstract | Ribosome biogenesis drives cell growth and proliferation, but mechanisms that modulate this process remain poorly understood. For a long time, small rRNA sequences have been widely treated as non-specific degradation products and neglected as garbage sequences. Recently, Prof. GUANG’s team identified a new class of antisense ribosomal siRNAs (risiRNAs) that downregulate pre-rRNA through the nuclear RNAi pathway in C. elegans.In this talk, Prof. GUANG will show the generation, function, and mechanism of this new class of small interfering RNAs. |