聯絡信息

職稱
系主任(生物醫學系), 教授
辦公室
(辦公室) E12-2063
/(實驗室) E12-3071
電話
(辦公室) +853 8822 4991
/ (實驗室) +853 8822 9120
傳真
+853 8822 2314
諮詢時間
星期二, 三 10:00 – 11:00
教學
研究團隊
Education | |
Knowledge Transfer Partnership (KTP) Postdoctoral Fellow | Queen’s University Belfast, UK (2004-2007) |
PhD in Biomedical Sciences | University of Ulster, UK (2003) |
BSc (1st Class Hons) in Biotechnology | University of Ulster, UK (2000) |
NVQ Level 4 (Higher National Diploma) in Management | Chartered Management Institute, UK (2007) |
Positions | |
2024 – Present | Professor, Faculty of Health Sciences, University of Macau |
2022 – Present | Fellow of the Royal Society of Chemistry (FRSC), UK |
2022 – Present | Fellow of the Royal Society of Biology (FRSB), UK |
2018 – 2024 | Associate Professor, Faculty of Health Sciences, University of Macau |
2013 – Present | Visiting Scientist/Mentor, Cancer Research UK Cambridge Institute, University of Cambridge, UK |
2014 – 2018 | Assistant Professor, Faculty of Health Sciences, University of Macau |
2007 – 2017 | Visiting Research Fellow, School of Pharmacy, Queen’s University Belfast, UK |
2011 – 2014 | Senior Research Associate / Fellow, Department of Oncology / Cancer Research UK Cambridge Institute, University of Cambridge, UK |
2007 – 2011 | Senior Scientist, Fusion Antibodies Ltd., UK |
Research Interests |
Prof. Kwok’s research interests mainly focus on developing novel monoclonal antibodies and natural biomolecules (including venom-based peptides, plant-derived molecules etc.) as prototype drugs for anticancer and anti-inflammatory therapies. In addition, Prof. Kwok’s research group also expands their research and scientific knowledge in the areas of existing and novel cancer biomarkers such as
in order to identify and validate their prognostic and therapeutic values according to the roles in hallmarks of cancer and chronic diseases.
For more details, please kindly further visit the Faculty of Health Sciences (FHS) Newsletter link — Principle Investigator (PI) Introduction Series and Prof. Kwok’s research group website as below: |
Representative Publications |
Journal Articles:
Books / Book Chapters:
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Research Grants | |
2024 | Dr. Stanley Ho Medical Development Foundation “Set Sail for New Horizons, Create the Future” Grant: Visiting Scholar Exchange Program |
2022 – Present | The Science and Technology Development Fund (FDCT), To investigate the molecular mechanisms of Osteopontin (OPN) and KRAS mutant/wild-type in colon cancer development and prognosis as an early diagnosis and therapeutic target |
2021 – Present | The Science and Technology Development Fund (FDCT) — National Natural Science Foundation of China (NSFC), Role and mechanism of animal venom peptide family BmKDfsin3/4 against HBV/HCV and the related-hepatocellular carcinoma mediated by p38 MAPK signal pathway |
2019 – 2022 | The Science and Technology Development Fund (FDCT), Novel combination treatment strategy with “Anti-ADAM17 Antibody + EGFR-TKi” for tackling the drug resistance issue in EGFR-mutant lung cancer |
2017 – 2020 | The Science and Technology Development Fund (FDCT), Discover & investigate the role of novel venom-based peptide(s) in cancer progression to unlock its mechanism as a therapeutic drug development to fight against cancer |
2017 – 2020 | The Science and Technology Development Fund (FDCT) — Minister of Science and Technology of China (MOST), Investigation of the correlation between PD-L1 expression and KRAS signaling pathway and its potential clinical application |
2015 – 2018 | The Science and Technology Development Fund (FDCT), Investigate the role of MCM10 in breast cancer progression & its potential as a therapeutic target |
2015 – 2018 | University of Macau Multi-Year Research Grant, A model system for structural and functional convergence of venom peptides: unlock a new era in drug development |
2015 – 2018 | University of Macau Multi-Year Research Grant, Osteopontin (OPN) expression as a prognostic indicator in colorectal cancer & its potential as a therapeutic target |
2014 – 2016 | University of Macau Start-Up Research Grant, Investigate novel regulator(s) for ADAM17 ectodomain shedding by cellular & proteomics approaches: Evaluation in biology and medicine |
2011 – 2016 | Cancer Research UK Research Grant (with Prof Gillian Murphy), Development of human TACE (mouse & human cross-reactive) therapeutic antibody against cancer |
2007 – 2011 | Invest Northern Ireland (NI) European Development Research Fund, Discovery, development & evaluation of the therapeutic efficacy of APO-1 antibody and human Cathepsin S antibody for the treatment of cancer |
2006 – 2009 | InterTrade Ireland Innova Grant, TB diagnostic kit/assay development |
2004 – 2007 | UK Technology Strategy Board KTP Funding, Define the shortfalls in current protein production techniques, and to develop novel techniques to permit more efficient and scaled protein engineering, protein expression and protein purification |
Patents |
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Awards | |
2024 | World’s Top 2% Scientists 2023 (Oncology & Carcinogenesis; Biochemistry & Molecular Biology) by Elsevier and Stanford University |
2022 – 2023 | Faculty of Health Sciences Best Teacher (Excellence in Research) Award |
2021 – 2022 | Faculty of Health Sciences Best Teacher (Overall Performance) Award |
2020 – 2021 | Cancer Biology & Medicine Outstanding Reviewer Award |
2020 | Incentive Award Scheme for Outstanding Academic Staff |
2019 – 2020 | Faculty of Health Sciences Best Teacher (Excellence in Service) Award |
2018 | Incentive Award Scheme for Outstanding Academic Staff |
2017 – 2018 | Faculty of Health Sciences Best Teacher (Excellence in Service) Award |
2014 | Winner of Protein Discovery Summit Poster Presentation: GTC’s 2nd Antibody & Protein Therapeutics Conference |
2011 – 2014 | CRUK Research Fellowship |
2008 | Winner of Knowledge Transfer Partnership (KTP) Regional Award |
2004 – 2007 | Knowledge Transfer Partnerships (KTP) Fellowship |
2000 – 2003 | Vice-Chancellor Research Scholarship |
1999 | University of Ulster Overseas student Bursary Award |
Professional Activities |
- Editor-in-Chief (Natural and Bio-inspired Molecules Section) – Biomolecules
- Executive Editor — Expert Reviews in Molecular Medicine
- Editor — PeerJ
- Associate Editor — Frontiers in Molecular Biosciences
- Associate Editor – Biology
- Frontiers Section Editor (Antibodies and Peptides in Cancer Therapy) — Recent Patents on Anti-Cancer Drug Discovery
- Guest Editor — Seminars in Cancer Biology (Thematic Issue: Regulating cell cycle-related activities: the right target for cancer therapy)
- Guest Editor — Pharmacological Research (Special Issue: Nano-/synthetic-based particles & natural-based biomolecules: Innovative drug design and delivery for potential pharmaceutical applications)
- Guest Editor — Toxins (Special Issue: Venom and Toxins as Targeted Therapy)
- Guest Editor — Scientific Reports (Collection: Therapeutic antibodies)
- Guest Editor — Biomolecules (Special Issue: Novel Natural-based Biomolecules Discovery for Tackling Chronic Diseases)
- Guest Editor — Biology (Special Issue: Proteases — From Basic Structure to Function to Drug Design as Targeted Therapy)
- Guest Editor — Molecules (Special Issue: Recent Advances in Natural Drug Discovery and Development – Is It a New Wave of Medicine?)
- Guest Editor — Biology (Special Issue: Recent Prototype Drug Development: Insights in Protein Science and Enzymology for Precision Medicine)
- Guest Editor — Frontiers in Pharmacology (Special Issue: New Mechanistic Insights into Cancer Precision Medicine)
- Guest Editor — Frontiers in Molecular Biosciences (Special Issue: Insights in Protein Chemistry and Enzymology: 2021)
- Guest Editor — Frontiers in Molecular Biosciences (Special Issue: Enzyme Inhibitors from Venoms and Plant Natural Biomolecules as Therapeutics)
- Guest Editor — Frontiers in Molecular Biosciences (Special Issue: ADAM, ADAMTS and Astacin Proteases: Challenges and Breakthroughs in the -Omics Era I & II)
- Guest Editor — Frontiers in Molecular Biosciences (Special Issue: Exercise and Cancer: From Clinical Association to Mechanistic Insights)
- Editorial Board Member of Toxins
- Editorial Board Member of BMC Medical Genomics
- Editorial Board Member of Biomolecules
- Editorial Board Member of Scientific Reports
- Editorial Board Member of Current Protein & Peptide Science
- Editorial Board Member of Cancer Biology & Medicine
- Editorial Board Member of Scientific Reports
- Advanced Science
- Advanced Composites and Hybrid Materials
- Applied Biochemistry and Biotechnology
- Analytical Cellular Pathology
- Aging
- ACS Omega
- Biology
- Biochemical Journal
- Biochemical Pharmacology
- BMC Cancer
- BMC Medical Genomics
- BMC Molecular Biology
- BMC Urology
- Breast Cancer Targets and Therapy
- Biochemical Society Transactions
- Biomedicine & Pharmacotherapy
- Biofactors
- Biomarkers in Medicine
- Bioscience Reports
- Biosensors and Bioelectronics
- Cells
- Cell Death and Disease
- Cancers
- Cancer Biomarkers
- Cancer Biology & Medicine
- Cancer Management & Research
- Cancer Medicine
- Cancer Informatics
- Cancer Letters
- Cancer Research
- Cellular and Molecular Life Sciences
- Cell Biology International
- Cellular Physiology and Biochemistry
- Computational & Structural Biotechnology Journal
- Communications Biology
- Current Pharmaceutical Biotechnology
- Current Drug Targets
- Current Protein & Peptide Science
- Current Enzyme Inhibition
- Current Oncology
- Cancer Biology & Treatment
- Drug Design, Development and Therapy
- Discover Oncology
- Experimental and Therapeutic Medicine
- Expert Opinion on Biological Therapy
- Expert Opinion on Drug Discovery
- European Journal of Pharmacology
- Future Oncology
- Global Challenges
- Heliyon
- Immunotherapy
- Immunology Letters
- International Immunopharmacology
- IUBMB Life
- International Journal of Biological Sciences
- International Journal of Biochemistry Research & Review
- International Journal of Nanomedicine
- International Journal of Oncology
- International Immunopharmacology
- Journal of Bone Oncology
- Journal of Cancer Metastasis and Treatment
- Journal of Cell Science & Therapy
- Journal of Cell Communication and Signaling
- Journal of Cellular and Molecular Medicine
- Journal of Clinical and Translational Research
- Journal of Experimental & Clinical Cancer Research
- Journal of Cancer
- Journal of Immunology
- Journal of Molecular Evolution
- Journal of Ovarian Research
- Journal of Pain Research
- Journal of Thoracic Disease
- Journal of Venom Research
- Journal of Venomous Animals and Toxins including Tropical Diseases
- Journal of Zhejiang University-SCIENCE B
- Langenbeck’s Archives of Surgery
- Life Sciences
- mAbs
- Marine Drugs
- Microorganisms
- Microbial Pathogenesis
- Medical Science Monitor
- Molecular Biotechnology
- Molecular Biology Reports
- Molecular Cancer Therapeutics
- Molecular Medicine Reports
- Molecular Therapy – Oncolytics
- Molecular Pain
- Molecules
- Mutation Research
- Oncogene
- OncoTargets & Therapy
- Oncology Reports
- Oncology Letters
- Oral Diseases
- Oxidative Medicine and Cellular Longevity
- PeerJ
- PLoS One
- PNAS
- Peptides
- Pharmaceuticals
- Pharmacology & Therapeutics
- Regulatory Peptide
- Research in Veterinary Science
- Seminars in Cancer Biology
- Scientific Reports
- Tissue Engineering
- Toxicology in Vitro
- Toxins
- Toxin Reviews
- Toxicon
- Theranostics
- Vaccines
- World Journal of Microbiology and Biotechnology
- World Journal of Surgical Oncology
- Book — Bioactive Natural Products, Elsevier, Amsterdam
- Book — Peptides in Molecular Pharmaceutics: Targeted Therapy and Drug Delivery, Nature Springer
- Book — Bioactive Natural Products, Elsevier, Amsterdam
- Book — Peptides in Molecular Pharmaceutics: Targeted Therapy and Drug Delivery, Nature Springer
- Book — Cancer Genomics and Human Health, Nature Springer
- Grant — Swiss National Science Foundation 2024, Switzerland
- Grant — Baptist University Initiation Grant for Faculty Niche Research Areas 2022/2023, Hong Kong
- Grant — Cancer Research UK (CRUK) Biotherapeutics Drug Discovery Programme 2020, UK
- Grant — Israeli Ministry of Science and Technology 2020, Israel
- Grant — The Wellcome Trust/DBT India Alliance Fellowship 2019, UK/India
- Grant — Breast Cancer Now 2017, UK
- Grant — Tyrolean Science Fund 2014/2015, Austria
- School of Pharmacy, Queen’s University Belfast, UK — PhD programme and MPhil programme
- Li Ka Shing Faculty of Medicine, University of Hong Kong — MMedSc programme
- Faculty of Medicine, Nursing & Health Sciences, Monash University, Australia — PhD programme
- School of Biomedical Sciences, Chinese University of Hong Kong – PhD programme
- School of Biological Sciences, University of Queensland, Australia — PhD programme
Others |
Conference Presentations
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