
Tue 10:00 – 11:00, Wed 16:00 – 17:00
Course Outlines
HSCI1003 General and Clinical Biochemistry HSCI4009 Toxicology
Name | Position | Office | Phone | |
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Pengchen CHEN | PhD Student | E12-3051 | +853 8822 4219 | |
Libin GUO | PhD Student | E12-3051 | +853 8822 4219 | |
Qiushuang WU | PhD Student | E12-3051 | +853 8822 4219 | |
Junnan LI | PhD Student | E12-3051 | +853 8822 4219 | |
Muhammad Jameel MUGHAL | PhD Student | E12-3051 | +853 8822 4219 | |
Weimin ZUO | PhD Student | E12-3051 | +853 8822 4219 | |
Jing LI | PhD Student | E12-3051 | +853 8822 4219 |
Education | |
Knowledge Transfer Partnership (KTP) Postdoctoral Fellow | Queen’s University Belfast, UK (2004-2007) |
PhD in Biomedical Sciences | University of Ulster, UK (2003) |
BSc (1st Class Hons) in Biotechnology | University of Ulster, UK (2000) |
NVQ Level 4 (Higher National Diploma) in Management | Chartered Management Institute, UK (2007) |
Positions | |
2018-Present | Associate Professor, Faculty of Health Sciences, University of Macau |
2013-present | Visiting Scientist, Cancer Research UK Cambridge Institute, University of Cambridge, UK |
2014-2018 | Assistant Professor, Faculty of Health Sciences, University of Macau |
2007-2017 | Visiting Research Fellow, School of Pharmacy, Queen’s University Belfast, UK |
2011-2014 | Senior Research Associate / Fellow, Department of Oncology / Cancer Research UK Cambridge Institute, University of Cambridge, UK |
2007-2011 | Senior Scientist, Fusion Antibodies Ltd., UK |
Research Interests |
Prof. Kwok’s research interests mainly focus on the development of novel monoclonal antibodies and natural biomolecules (including venom-based peptides, plant-derived molecules etc.) as prototype drugs for anticancer and anti-inflammatory therapies. In addition, Prof. Kwok’s research group also expands their research and scientific knowledge in the areas of existing and novel cancer biomarkers such as 1) matricellular protein — OPN, 2) metalloproteinase — ADAM17, ADAMTS5 and ADAMTS8, 3) DNA replication licensing factor — MCM proteins, 4) small GTP binding protein — RAN and RCC1, as well as immunotherapy markers (e.g. PD-1/PD-L1) in order to identify and validate their prognostic and therapeutic values according to the roles in hallmarks of cancer and chronic diseases. For more details, please kindly further visit the Faculty of Health Sciences (FHS) Newsletter link — Principle Investigator (PI) Introduction Series and/or Prof. Kwok’s research group website as below: https://mp.weixin.qq.com/s/jNol5GBHnYXzl6h2s6LL7Q http://www.henrykwoklab.com |
Representative Publications |
Journal Articles:
Books / Book Chapters:
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Grants | |
2019-2022 | The Science and Technology Development Fund (FDCT), Novel combination treatment strategy with “Anti-ADAM17 Antibody + EGFR-TKi” for tackling the drug resistance issue in EGFR-mutant lung cancer |
2017-2020 | The Science and Technology Development Fund (FDCT), Discover & investigate the role of novel venom-based peptide(s) in cancer progression to unlock its mechanism as a therapeutic drug development to fight against cancer |
2017-2020 | The Science and Technology Development Fund (FDCT) — Minister of Science and Technology of China (MOST), Investigation of the correlation between PD-L1 expression and KRAS signaling pathway and its potential clinical application |
2015-2018 | The Science and Technology Development Fund (FDCT), Investigate the role of MCM10 in breast cancer progression & its potential as a therapeutic target |
2015-2018 | University of Macau Multi-Year Research Grant, A model system for structural and functional convergence of venom peptides: unlock a new era in drug development |
2015–2018 | University of Macau Multi-Year Research Grant, Osteopontin (OPN) expression as a prognostic indicator in colorectal cancer & its potential as a therapeutic target |
2014-2016 | University of Macau Start-Up Research Grant, Investigate novel regulator(s) for ADAM17 ectodomain shedding by cellular & proteomics approaches: Evaluation in biology and medicine |
2011-2016 | Cancer Research UK Research Grant (with Prof Gillian Murphy), Development of human TACE (mouse & human cross-reactive) therapeutic antibody against cancer |
2007-2011 | Invest Northern Ireland (NI) European Development Research Fund, Discovery, development & evaluation of the therapeutic efficacy of APO-1 antibody and human Cathepsin S antibody for the treatment of cancer |
2006-2009 | InterTrade Ireland Innova Grant, TB diagnostic kit/assay development |
2004-2007 | UK Technology Strategy Board KTP Funding, Define the shortfalls in current protein production techniques, and to develop novel techniques to permit more efficient and scaled protein engineering, protein expression and protein purification |
Patents |
1. Kwok H. F., Rui M., Chen G. (2020) A venom-based peptide and its application. Patent CN 202010469590.8 |
Awards | |
2019-2020 | Incentive Award Scheme for Outstanding Academic Staff |
2017-2018 | Incentive Award Scheme for Outstanding Academic Staff |
2017-2018 | Faculty of Health Sciences Best Teacher (Excellence in Service) Award |
2014 | Winner of Protein Discovery Summit Poster Presentation: GTC’s 2nd Antibody & Protein Therapeutics Conference |
2011-2014 | CRUK Research Fellowship |
2008 | Winner of Knowledge Transfer Partnership (KTP) Regional Award |
2004-2007 | Knowledge Transfer Partnerships (KTP) Fellowship |
2000-2003 | Vice-Chancellor Research Scholarship |
1999 | University of Ulster Overseas student Bursary Award |
Professional Activities |
Invited Editorial Service:
Ad Hoc Invited Reviewer of Journal / Book / Grant:
Ad Hoc Invited External Examiner:
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Others |
Conference Presentations
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