周立強博士 - Faculty of Health Sciences (FHS)

stephaniepwng Ng Stephanie Pei Wen2024-04-08T14:59:28+08:002021-11-05|

聯絡信息

職稱

研究助理教授

辦公室

(辦公室)E12-1023

電話

(辦公室) +853 8822 2914

電郵

liqiangzhou@um.edu.mo

諮詢時間

星期二、四 10:00 – 11:00

教學

Education
MD	Huazhong University of Science and Technology
BMed	Huazhong University of Science and Technology

Positions
2022 – Present	Research Assistant Professor, Faculty of Health Sciences, University of Macau
2021 – 2022	Postdoc/RA, Faculty of Health Sciences, University of Macau

Research Interests
Precision oncology theranostics based on advanced nanotechnology and medical AI imaging.

Representative Publications
Zhou, L. Q., Wu, X. L., Huang, S. Y., Wu, G. G., Ye, H. R., Wei, Q., Bao, L. Y., Deng, Y. B., Li, X. R., Cui, X. W., & Dietrich, C. F. Lymph node metastasis prediction from primary breast cancer US images using deep learning. Radiology. 2020; 294(1):19-28. (ESI Highly Cited Paper) Zhou, L. Q., Lyu, J. X., Liu, F., Su, Y. H, Feng, L., Zhang, X. J. , Immunogenic PANoptosis-initiated Cancer Sono-Immune Reediting Nanotherapy by Iteratively Boosting Cancer Immunity Cycle. Advanced Materials 2023, 2305361. Zhou, L.Q., Li, K., Liu, Y.Y., Zhang, R.J., Yao, Y.C., Chen, Q.Q., Xie, D., Zhang, X.J.. Living Cell-derived Intelligent Nanobots for Precision Oncotherapy.Advanced Functional Materials. 2023, 2311857. Zhou, L. Q., Feng, W., Chen, L., Huang, H., Huang, S. J., Chen, Q., Zhang, X. J., & Chen, Y.. Targeting acidogenic metabolism by engineering self-catalytic siRNA nanocarriers/nanocatalysts for amplified tumor apoptosis/ferroptosis. *Nano Today.* 2022; 46:101623 Zhou, L. Q., Feng, W., Mao, Y. H., Chen, Y., and Zhang, X. J.. Nanoengineered Sonosensitive Platelets for Synergistically Augmented Sonodynamic Tumor Therapy by Glutamine Deprivation and Cascading Thrombosis. *Bioactive Materials* 2023; 24, 26-36 Zhou, L. Q., Dong, C. H., Ding, L., Feng, W., Yu, L. D., Cui, X. W., & Chen, Y.. Targeting ferroptosis synergistically sensitizes apoptotic sonodynamic antitumor nanotherapy. Nano Today.* 2021; 39:101212. Chen, Y.M.F., Luo, Z., Meng, W., Liu, K., Chen, Q.Q., Cai, Y., Ding, Z., Huang, C., Zhou, Z.K., Jiang, M., & Zhou, L.Q., Decoding the “Fingerprint” of Implant Materials: Insights into the Foreign Body Reaction.Small 2024, 2310325. Zeng, Q. H.¹, Ma, X.Y.¹, Song, Y.M.H., Chen Q.Q., Jiao Q.L., & Zhou, L. Q., Targeting regulated cell death in tumor nanomedicines. Theranostics* 2022; 12(2): 817-841. (*ESI Highly Cited Paper) Zhou, L. Q., Huo, M. F., Qian, X. Q., Ding, L., Yu, L. D., Feng, W., Cui, X. W., & Chen, Y.. Autophagy blockade synergistically enhances nanosonosensitizer-enabled sonodynamic cancer nanotherapeutics. *Journal of Nanobiotechnology* 19, 112, 2021. Zhou, L. Q., Li, P., Cui, X. W., & Dietrich, C. F. Ultrasound nanotheranostics in fighting cancer: Advances and prospects. Cancer Letters.* 2020; 470:204-219. Xu, M.¹, Zhou, L. Q.^1, , Zheng, L., Zhou, Q., Liu, K., Mao, Y., & Song, S. Sonodynamic therapy-derived multimodal synergistic cancer therapy. *Cancer Letters.* 2021; 497:229-242. (*ESI Highly Cited Paper) Zhou, L. Q.,* Zeng, S. E., Xu, J. W., Lv, W. Z., Mei, D., Tu, J. J., J, F., Cui, X. W., Dietrich, C. F. Deep learning predicts cervical lymph node metastasis in clinically node-negative papillary thyroid carcinoma. *Insights into Imaging. 2023; 14, 222. Zhou, L. Q.,* Wang, J. Y., Yu, S. Y., Wu, G. G., Wei, Q., Deng, Y. B., Wu, X. L., Cui, X. W., & Dietrich, C. F. Artificial intelligence in medical imaging of the liver. World Journal of Gastroenterology. 2019*;25(6):672-682.

Representative Publications

Zhou, L. Q., Wu, X. L., Huang, S. Y., Wu, G. G., Ye, H. R., Wei, Q., Bao, L. Y., Deng, Y. B., Li, X. R., Cui, X. W.*, & Dietrich, C. F. Lymph node metastasis prediction from primary breast cancer US images using deep learning. Radiology. 2020; 294(1):19-28. (ESI Highly Cited Paper)
Zhou, L. Q., Lyu, J. X., Liu, F., Su, Y. H, Feng, L., Zhang, X. J. *, Immunogenic PANoptosis-initiated Cancer Sono-Immune Reediting Nanotherapy by Iteratively Boosting Cancer Immunity Cycle. Advanced Materials 2023, 2305361.
Zhou, L.Q.*, Li, K., Liu, Y.Y., Zhang, R.J., Yao, Y.C., Chen, Q.Q., Xie, D.*, Zhang, X.J.*. Living Cell-derived Intelligent Nanobots for Precision Oncotherapy.Advanced Functional Materials. 2023, 2311857.
Zhou, L. Q., Feng, W., Chen, L., Huang, H., Huang, S. J., Chen, Q.*, Zhang, X. J.*, & Chen, Y.*. Targeting acidogenic metabolism by engineering self-catalytic siRNA nanocarriers/nanocatalysts for amplified tumor apoptosis/ferroptosis. Nano Today. 2022; 46:101623
Zhou, L. Q., Feng, W., Mao, Y. H., Chen, Y.*, and Zhang, X. J.*. Nanoengineered Sonosensitive Platelets for Synergistically Augmented Sonodynamic Tumor Therapy by Glutamine Deprivation and Cascading Thrombosis. Bioactive Materials 2023; 24, 26-36
Zhou, L. Q., Dong, C. H., Ding, L.*, Feng, W., Yu, L. D., Cui, X. W.*, & Chen, Y.*. Targeting ferroptosis synergistically sensitizes apoptotic sonodynamic antitumor nanotherapy. Nano Today. 2021; 39:101212.
Chen, Y.M.F., Luo, Z., Meng, W., Liu, K., Chen, Q.Q., Cai, Y., Ding, Z., Huang, C., Zhou, Z.K.*, Jiang, M.*, & Zhou, L.Q.*, Decoding the “Fingerprint” of Implant Materials: Insights into the Foreign Body Reaction.Small 2024, 2310325.
Zeng, Q. H.¹, Ma, X.Y.¹, Song, Y.M.H., Chen Q.Q., Jiao Q.L.*, & Zhou, L. Q.*, Targeting regulated cell death in tumor nanomedicines. Theranostics 2022; 12(2): 817-841. (ESI Highly Cited Paper)
Zhou, L. Q., Huo, M. F., Qian, X. Q., Ding, L.*, Yu, L. D., Feng, W., Cui, X. W.*, & Chen, Y.*. Autophagy blockade synergistically enhances nanosonosensitizer-enabled sonodynamic cancer nanotherapeutics. Journal of Nanobiotechnology 19, 112, 2021.
Zhou, L. Q., Li, P., Cui, X. W.*, & Dietrich, C. F. Ultrasound nanotheranostics in fighting cancer: Advances and prospects. Cancer Letters. 2020; 470:204-219.
Xu, M.¹, Zhou, L. Q.^1, *, Zheng, L., Zhou, Q., Liu, K., Mao, Y., & Song, S*. Sonodynamic therapy-derived multimodal synergistic cancer therapy. Cancer Letters. 2021; 497:229-242. (ESI Highly Cited Paper)
Zhou, L. Q., Zeng, S. E., Xu, J. W., Lv, W. Z., Mei, D., Tu, J. J., J, F., Cui, X. W., Dietrich, C. F. Deep learning predicts cervical lymph node metastasis in clinically node-negative papillary thyroid carcinoma. Insights into Imaging. 2023; 14, 222.
Zhou, L. Q., Wang, J. Y., Yu, S. Y., Wu, G. G., Wei, Q., Deng, Y. B., Wu, X. L., Cui, X. W.*, & Dietrich, C. F. Artificial intelligence in medical imaging of the liver. World Journal of Gastroenterology. 2019;25(6):672-682.

Research Grants
Macau Science and Technology Development Fund (0032/2023/ITP1) National Natural Science Foundation of China (82302369) Ministry of Education Frontiers Science Centre for Precision Oncology, University of Macau (FHS-FSCPO/011/2023)

Awards
2018-2022 Ranking of top 100 Chinese experts with academic influence in the field of Medicine, Medicial Ultrasound (No. 64)

Professional Activities
Young Editorial Board Member of Asian Journal of Pharmaceutical Sciences (IF: 10.2) Young Editorial Board Member of VIEW (IF: 8.6) Outstanding Young Editorial Board Member of BMEMat Young Editorial Board Member of iRADIOLOGY Reviewer for AJPS, Small Methods, Journal of Advanced Research, Cancer Letters, Medical Physics, Clinical Breast Cancer, Heliyon, and other SCI journals