2023-01-16T14:23:21+08:002023-01-16|Publish|
  1. Wang JC, Chen DP, Lu SX, Chen JB, Wei Y, Liu XC, Tang YH, Zhang R, Chen JC, Kan A, Xu L, Zhang YJ, Hou J, Kuang DM, Chen MS, Zhou ZG. PIM2 Expression Induced by Proinflammatory Macrophages Suppresses Immunotherapy Efficacy in Hepatocellular Carcinoma. Cancer Research. 2022 Sep 16;82(18):3307-3320. doi: 10.1158/0008-5472.CAN-21-3899
  2. Hou J, Karin M, Sun B. Targeting cancer-promoting inflammation – have anti-inflammatory therapies come of age? Nature Reviews Clinical Oncology. 2021 May;18(5):261-279. doi: 10.1038/s41571-020-00459-9
  3. Ng SS, De Labastida Rivera F, Yan J, Corvino D, Das I, Zhang P, Kuns R, Chauhan SB, Hou J, Li XY, Frame TCM, McEnroe BA, Moore E, Na J, Engel JA, Soon MSF, Singh B, Kueh AJ, Herold MJ, Montes de Oca M, Singh SS, Bunn PT, Aguilera AR, Casey M, Braun M, Ghazanfari N, Wani S, Wang Y, Amante FH, Edwards CL, Haque A, Dougall WC, Singh OP, Baxter AG, Teng MWL, Loukas A, Daly NL, Cloonan N, Degli-Esposti MA, Uzonna J, Heath WR, Bald T, Tey SK, Nakamura K, Hill GR, Kumar R, Sundar S, Smyth MJ, Engwerda CR. The NK cell granule protein NKG7 regulates cytotoxic granule exocytosis and inflammation. Nature Immunology. 2020 Oct;21(10):1205-1218. doi: 10.1038/s41590-020-0758-6.
  4. Chauvin JM, Ka M, Pagliano O, Menna C, Ding Q, DeBlasio R, Sanders C, Hou J, Li XY, Ferrone S, Davar D, Kirkwood JM, Johnston RJ, Korman AJ, Smyth MJ, Zarour HM. IL15 Stimulation with TIGIT Blockade Reverses CD155-mediated NK-Cell Dysfunction in Melanoma. Clinical Cancer Research. 2020 Oct 15;26(20):5520-5533. doi: 10.1158/1078-0432.CCR-20-0575.
  5. Whyte CE, Osman M, Kara EE, Abbott C, Foeng J, McKenzie DR, Fenix KA, Harata-Lee Y, Foyle KL, Boyle ST, Kochetkova M, Aguilera AR, Hou J, Li XY, Armstrong MA, Pederson SM, Comerford I, Smyth MJ, McColl SR. ACKR4 restrains antitumor immunity by regulating CCL21. Journal of Experimental Medicine. 2020 Jun 1;217(6):e20190634. doi: 10.1084/jem.20190634.
  6. Hou J, Zhang H, Sun B, Karin M. The immunobiology of hepatocellular carcinoma in humans and mice: basic concepts and therapeutic implications. Journal of Hepatology. 2020 Jan;72(1):167-182. doi: 10.1016/j.jhep.2019.08.014.
  7. Wang J, Hu B, Zhang He, Zhao Zhenjun, Zhao Zhicong, Zhang Haiyan, Ma X, Shen B, Sun B, Huang X, Hou J (co-corresponding), Xia Q. Intracellular XBP1-IL-24 axis dismantles CHOP-mediated cytotoxic unfolded protein response in the liver. Cell Death & Disease. 2020 Jan;11(1):17. doi: 10.1038/s41419-019-2209-6.
  8. Hou J (co-corresponding), Zhang He, Liu J, Zhao Zhenjun, Wang J, Lu Z, Hu B, Zhou J, Zhao Zhicong, Feng M, Zhang Haiyan, Shen B, Huang X, Sun B, He C, Xia Q. YTHDF2 reduction fuels inflammation and vascular abnormalization in hepatocellular carcinoma. Molecular Cancer 2019 Nov;18(1):163. doi: 10.1186/s12943-019-1082-3.
  9. Hou J, Greten T, Xia Q. Immunosuppressive cell death in cancer. Nature Reviews Immunology. 2017 Jun;17(6):401. doi: 10.1038/nri.2017.46.
  10. Hou J, Deng L, Zhuo H, Lin Z, Chen Y, Jiang R, Chen D, Zhang X, Huang X, Sun B. PTPROt maintains tumor immunity in the microenvironment of hepatocellular carcinoma. Journal of Molecular Cell Biology. 2015 Aug;7(4):338-50. doi: 10.1093/jmcb/mjv047.
  11. Jiang R, Chen D, Hou J, Tan Z, Wang Y, Huang X, Wang X, Sun B. Survival and inflammation promotion effect of PTPRO in fulminant hepatitis is associated with NF-κB activation. Journal of Immunology. 2014 Nov 15;193(10):5161-70. doi: 10.4049/jimmunol.1303354.
  12. Hou J, Xia Y, Jiang R, Cheng D, Xu J, Deng L, Huang X, Wang X, Sun B. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-κB. Journal of Hepatology. 2014 Feb;60(2):306-12. doi: 10.1016/j.jhep.2013.09.028.
  13. Jiang R, Wang H, Deng L, Hou J, Shi R, Yao M, Gao Y, Yao A, Wang X, Yu L, Sun B. IL-22 is related to development of human colon cancer by activation of STAT3. BMC Cancer. 2013 Feb 5;13:59. doi: 10.1186/1471-2407-13-59.
  14. Chen C, Hou J (co-first author), Lin Z, Yao M, Jiang R, Wang Y, Gao Y, Shao Q, Deng L, Chen Y, Sun B. A bystander cell-based GM-CSF secreting vaccine synergizes with a low dose of cyclophosphamide and induces therapeutic immune responses against murine hepatocellular carcinoma. Cellular & Molecular Immunology. 2013 Jun;10(4):349-59. doi: 10.1038/cmi.2013.20.
  15. Hou J, Xu J, Jiang R, Wang Y, Chen C, Deng L, Huang X, Wang X, Sun B. Estrogen sensitive PTPRO expression represses hepatocellular carcinoma progression by control of STAT3. Hepatology. 2013 Feb;57(2):678-88. doi: 10.1002/hep.25980.