2025-09-11T15:00:59+08:002024-05-02|
Contact Information
Title
UM Macao Fellow
Office
(Address) E12-1040
Email
wengianche@um.edu.mo
Teaching
Education
PhD Karolinska Institutet, Sweden, 2024
Msc Karolinska Institutet, Sweden, 2018
Bsc University of Macau, China, 2016
Position
04/2024 – Present UM Macao Fellow, Faculty of Health Sciences, University of Macau
06/2018 – 12/2019 Research Assistant, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden
Research Interests
  1. Public health
  2. Data science
Representative Publications
  1. Che WI, Baecklund F, Hellgren K, Kuja-Halkola R, Lundberg IE, Westerlind H, Holmqvist M. Familial Co-Aggregation of Idiopathic Inflammatory Myopathies and Cancer: A Swedish Population-Based Study. Arthritis & Rheumatology. 2023 Aug;75(8):1445-1455. doi: 10.1002/art.42493. Epub 2023 May 8. PMID: 36908049.
  2. Che WI, Lundberg IE, Holmqvist M. Environmental Risks for Inflammatory Myopathies. Rheum Disease Clinics of North America. 2022 Nov;48(4):861-874. doi: 10.1016/j.rdc.2022.06.007. PMID: 36333000.
  3. Che WI, Westerlind H, Lundberg IE, Hellgren K, Kuja-Halkola R, Holmqvist ME. Familial autoimmunity in patients with idiopathic inflammatory myopathies. Journal of Internal Medicine. 2023 Feb;293(2):200-211. doi: 10.1111/joim.13573. Epub 2022 Oct 10. PMID: 36165332; PMCID: PMC10092836.
  4. Che WI, Westerlind H, Lundberg IE, Hellgren K, Kuja-Halkola R, Holmqvist M. Familial aggregation and heritability: a nationwide family-based study of idiopathic inflammatory myopathies. Annals of the Rheumatic Diseases. 2021 Nov;80(11):1461-1466. doi: 10.1136/annrheumdis-2021-219914. Epub 2021 Jun 15. PMID: 34130985; PMCID: PMC8522465.
  5. Dani L, Ian Che W, Lundberg IE, Hellgren K, Holmqvist M. Overall and site- specific cancer before and after diagnosis of idiopathic inflammatory myopathies: A nationwide study 2002-2016. Seminar in Arthritis Rheumatism. 2021 Feb;51(1):331-337. doi: 10.1016/j.semarthrit.2020.12.009. Epub 2020 Dec 24. PMID: 33508731.
  6. Xu DD, Rao WW, Cao XL, Wen SY, An FR, Che WI, Bressington DT, Cheung T, Ungvari GS, Xiang YT. Prevalence of depressive symptoms in primary school students in China: A systematic review and meta-analysis. Journal of Affective Disordors. 2020 May 1;268:20-27. doi: 10.1016/j.jad.2020.02.034. Epub 2020 Feb 19. PMID: 32158003.
  7. Che WI, Hellgren K, Stephansson O, Lundberg IE, Holmqvist M. Pregnancy outcomes in women with idiopathic inflammatory myopathy, before and after diagnosis-a population-based study. Rheumatology (Oxford). 2020 Sep 1;59(9):2572-2580. doi: 10.1093/rheumatology/kez666. PMID: 31998957; PMCID: PMC7449806.
  8. Che WI, Hellgren K, Lundberg IE, Holmqvist M. Reproductive Pattern in Women with Idiopathic Inflammatory Myopathy: A Population-based Study. Journal of Rheumatology. 2020 Sep 1;47(9):1392-1396. doi: 10.3899/jrheum.190474. Epub 2019 Aug 15. PMID: 31416924.
  9. Rao WW, Xu DD, Cao XL, Wen SY, Che WI, Ng CH, Ungvari GS, He F, Xiang YT. Prevalence of depressive symptoms in children and adolescents in China: A meta- analysis of observational studies. Psychiatry Research. 2019 Feb;272:790-796. doi: 10.1016/j.psychres.2018.12.133. Epub 2018 Dec 25. PMID: 30832200.
  10. Xu DD, Rao WW, Cao XL, Wen SY, Che WI, Ng CH, Ungvari GS, Du Y, Zhang L, Xiang YT. Prevalence of major depressive disorder in children and adolescents in China: A systematic review and meta-analysis. Journal of Affective Disordors. 2018 Dec 1;241:592-598. doi: 10.1016/j.jad.2018.07.083. Epub 2018 Aug 1. PMID: 30172211.
  11. Liu LJ, He B, Miles JA, Wang W, Mao Z, Che WI, Lu JJ, Chen XP, Wilson AJ, Ma DL, Leung CH. Inhibition of the p53/hDM2 protein-protein interaction by cyclometallated iridium(III) compounds. Oncotarget. 2016 Mar 22;7(12):13965-75. doi: 10.18632/oncotarget.7369. PMID: 26883110; PMCID: PMC4924691.
  12. Leung KH, Liu LJ, Lin S, Lu L, Zhong HJ, Susanti D, Rao W, Wang M, Che WI, Chan DS, Leung CH, Chan PW, Ma DL. Discovery of a small-molecule inhibitor of STAT3 by ligand-based pharmacophore screening. Methods. 2015 Jan;71:38-43. doi: 10.1016/j.ymeth.2014.07.010. Epub 2014 Aug 24. PMID: 25160651.
Awards
2022 Abstract Award for abstract entitled “Familial associations of autoimmune diseases in patients
with idiopathic inflammatory myopathies – A Swedish population-based study”, the 4th Global
Conference on Myositis, Prague, Czech Republic
2022 Travel Grant, Karolinska Institutet
2015 Spring 2015 Dean’s List, College of Education at the University of Illinois at Urbana-Champaign
2014 Rector’s Honor List for Academic Year 2013/2014, University of Macau
2014 Dean’s Honor List, Institute of Chinese Medical Sciences, University of Macau
2013 Second place of 13th Challenge Cup National Undergraduate Curricular Academic Science and
Technology Contest, China
2013 Dean’s Honor List, Institute of Chinese Medical Sciences, University of Macau
Professional Activities
  • Affiliated to research, Karolinska Institutet, Stockholm, Sweden