2020-12-15T18:21:45+08:002020-03-06|Publish|
Full publications
Journal Articles:

2020

  • Chen Y., Li B., Lyu P., Kwok H. F., Ge L., Wu Q. (2020) Boronate ester bond-based potentiometric aptasensor for screening carcinoembryonic antigen-glycoprotein using nanometer-sized CaCO3 with ion-selective electrode. Analytical and Bioanalytical Chemistry https://doi.org/10.1007/s00216-020-03067-9
  • Xie J., Chen P., Xie. X, Sun Y., Huang Z., Wei R., Maio Z., Wang Q., Zhang S. D., Wong K. H., Lin Y.*, Huang C.*, Kwok H. F.* (2020)  Exploration of Gastric Neuroendocrine Carcinoma (GNEC) specific signaling pathways involved in chemoresistance via transcriptome and in vitro Computational and Structural Biotechnology Journal 18: 2610-2620.
  • Ma R., Kwok H. F.* (2020) New opportunities and challenges of venom-based and bacteria-derived molecules for anticancer therapy. Seminars in Cancer Biology (In Press) https://doi.org/10.1016/j.semcancer.2020.08.010.
  • Zhou X., Liu Y., Gao Y., Wang Y., Xia Q., Zhong R., Ma C., Zhou M., Xi X.*,  Shaw C., Chen T., Wu D., Kwok H. F.*, Wang L. (2020) Enhanced Antimicrobial Activity of N-Terminal Derivatives of a Novel Brevinine-1 Peptide from The Skin Secretion of Odorrana schmackeri. Toxins 12(8): 484.
  • Yang S., Cao B., Zhou G., Zhu L., Wang L., Zhang L., Kwok H. F., Zhang Z., Zhao Q. (2020) Targeting the B7-H3 Immune Checkpoint with Specific CAR-engineered NK-92 Cells Exhibits Potent Cytotoxicity against Non-Small Cell Lung Cancer. Frontiers in Pharmacology 11: 1089.
  • Gutsaeva D. R., Shalaby L., Powell F. L., Thounaojam M. C., Abouhish H., Wetzstein S. A., Jadeja R. N., Kwok H. F., Martin P. M., Bartoli M. (2020) Inactivation of Endothelial ADAM17 Reduces Retinal Ischemia-Reperfusion Induced Neuronal and Vascular Damage. International Journal of Molecular Sciences 21(15): 5379.
  • Zhou X., Xu J., Zong R., Ma C., Zhou M., Cao Z., Xi X.*, Shaw C., Chen T., Wang L., Kwok H. F.* (2020) Pharmacological Effects of a Novel Bradykinin-Related Peptide (RR-18) from the Skin Secretion of the Hejiang Frog (Ordorrana hejiangensis) on Smooth Muscle. Biomedicines 8(7): 225.
  • Ma R., Ren Z., Li B., Siu S. W. I., Chen G., Kwok H. F.* (2020) Novel venom-based peptides (P13 & its derivative — M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGF-ß signaling pathways. Stem Cell Research & Therapy 11: 243.
  • Guo L., Wei R., Lin Y.*, Kwok H. F.* (2020) Clinical and recent patents applications of PD-1/PD-L1 targeting immunotherapy in cancer treatment — current progress, strategy and future perspective. Frontiers in Immunology (In Press)
  • Ma R., Ren Z., Li B., Siu S. W. I., Chen G., Kwok H. F.* (2020) Novel venom-based peptides (P13 & its derivative — M6) to maintain self-renewal of human embryonic stem cells by activating FGF and TGF-ß signaling pathways. Stem Cell Research & Therapy 11: 243.
  • Li J., Kwok H. F.* (2020) Current strategies for treating NSCLC: from biological mechanisms to clinical treatment. Cancers 12(6): 1587.
  • Yueng L., Anderson J. M. L., Wee J. L., Demaria M. C., Finsterbusch M., Liu Y. S., Hall P., Smith B. C., Danker W., Elgss K., Wicks I. P., Kwok H. F., Wright M. D., Hickey M. (2020) Leukocyte tetraspanin CD53 restrains α3 integrin mobilization and facilitates cytoskeletal remodelling and transmigration in mice. Journal of Immunology 205: 10.4049/jimmunol.1901054.
  • Wu Q., Wong J. P. C., Kwok H. F.* (2020) Putting the brakes on tumorigenesis with natural products of plant origin: Insights into the molecular mechanisms of actions and immune targets for bladder cancer treatment. Cells 9(5): 1213.
  • Demaria M. C., Yeung L., Peeters R., Wee J. L., Mihaljcic M., Jones E. L., Nasa Z., Alderuccio F., Hall P., Smith B. C., Binger K. J., Hammerling G., Kwok H. F., Newman A., Ager A., van Spriel A., Hickey M. J., Wright M. D. (2020) Tetraspanin CD53 promotes lymphocyte recirculation by stabilising L-selectin surface expression. iScience 23(5): 101104.
  • Xie S., Li B., Lyu P., Kwok H. F., Ge L., Wu Q. (2020) A new voltammetric immunosensing platform for prostate-specific antigen based on the Cu(II)-pyrophosphate ion chelation reaction. New Journal of Chemistry 44: 3820-3823.
  • Shalaby L., Thounaojam M., Tawfik A., Li J., Hussein K., Jahng J. W., Al-Shabrawey M., Kwok H. F., Bartoli M., Gutsaeva, D. (2020) Role of endothelial ADAM17 in early vascular changes associated with diabetic retinopathy. Journal of Clinical Medicine 9(2): 400.
  • Scheib H., Nekaris A., Rode J., Ragnarsson L., Baumann K., Dobson J., Wirdateti W., Nouwens A., Nijman V., Martelli P., Ma R., Lewis R., Kwok H. F.* and Fry B.* (2020) A Structural comparison of the cat dander allergenic protein Fel d1 and the brachial gland secretion protein from the Javan slow loris Nycticebus javanicus. Toxins 12(2): 86.
  • Cheng Y., Sun F., Li S., Gao M., Wang L., Sarhan M., Abdel-Rahman M. A., Li W., Kwok H. F., Wu Y. and Cao Z. (2020) Inhibitory Activity of a Scorpion Defensin BmKDfsin3 against Hepatitis C Virus. Antibiotics 9(1): 33.
  • Ma R., Wong S. W., Ge L., Shaw C., Siu S. W. I. and Kwok H. F.* (2020) In vitro & molecular dynamic stimulation study to explore physicochemical parameters for antibacterial peptide to become potent anticancer peptide. Molecular Therapy — Oncolytics 16: 7-19.

2019

  • Yang Z., Chan K. I., Kwok H. F.* and Tam K. Y.* (2019) Novel Therapeutic Anti-ADAM17 Antibody A9(B8) Enhances EGFR-TKI–Mediated Anticancer Activity in NSCLC. Translational Oncology 12(11): 1516-1524.
  • Zhou X., Shi D., Zhong R., Ye Z., Ma C., Zhou M., Xi X., Wang L., Chen T. and Kwok H. F.* (2019) Bioevaluation of Ranatuerin-2Pb from the Frog Skin Secretion of Rana pipiens and its Truncated Analogues. Biomolecules 9(6): 249.
  • Bin L., Peng L., Xie S., Qin H., Pu W., Xu H., Chen T., Shaw C., Ge L.* and Kwok H. F.* (2019) LFB: A novel antimicrobial Brevinin-like peptide from the skin secretion of the Fujian large headed frog, Limnonectes fujianensi. Biomolecules 9(6): 242.
  • Chen P., Wang Q., Xie J.* and Kwok H. F.* (2019) Signaling networks and the feasibility of computational analysis in gastroenteropancreatic neuroendocrine tumors. Seminars in Cancer Biology 58: 80-89.
  • Debono J., Bos M. H. A., Coimbra F., Frank N., Kwok H. F.* and Fry B. G.* (2019) Basal but divergent: Clinical implications of differential coagulotoxicity in a clade of Asian vipers. Toxicology In Vitro 58: 195-206.
  • Ge L., Li B., Xu H., Pu W. and Kwok H. F.* (2019) Backfilling rolling cycle amplification with enzyme-DNA conjugates on antibody for portable electrochemical immunoassay with glucometer readout. Biosensors and Bioelectronics 132: 210-216.
  • Li B., Pu W, Xu H., Ge L.*, Kwok H. F.* and Hu L. (2019) Magneto-controlled flow-injection device for electrochemical immunoassay of alphafetoprotein on magnetic beads using redox-activeferrocene derivative polymer nanospheres. Analyst 144: 1443-1441.
  • Lyu P. and Kwok H. F.* (2019) High-throughput strategy accelerates the progress of marine anticancer peptide drug development. Recent Patents on Anti-Cancer Drug Discovery 14(1): 2-4.
  • Liu M., Liu X., Huang Z., Tang X., Lin X., Xu Y., Kwok H. F.*, Lin Y.* and Feng S* (2019) Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy. Journal of Biophotonics 12(3): e201800332.

2018

  • Jameel Mughal M., Mahadevappa R and Kwok H. F.* (2018) DNA replication licensing proteins: saints and sinners in cancer. Seminars in Cancer Biology 58: 11-21
  • Debono J., Bos M. H. A., Nouwens A., Ge L., Frank N. and Kwok H. F.* and Fry B. G.* (2018) Habu coagulotoxicity: Clinical implications of the functional diversification of Protobothrops snake venoms upon blood clotting factors. Toxicology In Vitro 55: 62-74.
  • Rajendran B. K., Suresh M. X., Bhaskaran S. P., Harshitha Y., Gaur U. and Kwok H. F.* (2018) Pharmacoinformatic approach to explore the antidote potential of phytochemicals on bungarotoxin from Indian krait, Bangarus caeruleus. Computational and Structural Biotechnology Journal 16: 450-461.
  • Wei R., Guo L., Wang Q., Miao J., Kwok H. F.* and Lin Y.* (2018) Targeting PD-L1 Protein: Translation, Modification and Transport. Current Protein and Peptide Science 20: 82-91.
  • Lyu P., Ge L., Ma R., Wei R., McCrudden C. M., Chen T., Shaw C. and Kwok H. F.* (2018) Identification and pharmaceutical evaluation of novel frog skin-derived serine proteinase inhibitor peptide — PE-BBI (Pelophylax esculentus Bowman-Birk inhibitor) for the potential treatment of cancer. Scientific Reports 8(1):14502.
  • Mahadevappa R., Neves H., Yuen S. M., Jameel M., Bai Y., Yuen H. F., Zhang S. D., Zhu Y., Lin Y. and Kwok H. F.* (2018) DNA replication licensing protein MCM10 promotes tumor progression and is a novel prognostic biomarker and potential therapeutic target in breast cancer. Cancers 10(9): 282.
  • Tin Y., Chen X., Ma C., Xi X., Wang L., Zhou M., Burrows J. F. and Kwok H. F. and Chen T. (2018) Biological Activities of Cationicity-Enhanced and Hydrophobicity-Optimized Analogues of an Antimicrobial Peptide, Dermaseptin-PS3, from the Skin Secretion of Phyllomedusa sauvagii. Toxins 10(8): 320.
  • Li B., Lyu P., Xi X., Ge L., Mahadevappa R., Shaw C. and Kwok H. F.* (2018) Triggering of cancer cell cycle arrest by a novel scorpion venom-derived peptide — Gonearrestide. Journal of Cellular and Molecular Medicine 22(9) 4460-4473.
  • Coimbra F. C. P., Dobson J., Zdenek C. N., Op den Brouw B., Hamilton B., Debono J., Masci P., Frank N., Ge L, Kwok H. F. and Fry B. G. (2018) Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands. Comp Biochem Physiol C Toxicol Pharmacol 211: 7-14.
  • Wei R., Wong J. P. C., Lyu P., Xi X., Tong O. L. H., Zhang S. D., Yuen H. F., Shirasawa S. and Kwok H. F.* (2018) In vitro and clinical data analysis of Osteopontin as a prognostic indicator in colorectal cancer. Journal of Cellular and Molecular Medicine 22(9): 4097-4105.
  • Huang Y., Zhang Y., Ge L., Lin Y.* and Kwok H. F.* (2018). The Role of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma. Cancers 10(3): 82.
  • Goldenberg J., Cipriani V., Jackson T. N. W., Arbuckle K., Debono J., Dashevsky D., Panagides N., Ikonomopoulou M. P., Koludarov I., Li B., Santana R. C., Nouwens A., Jones A., Hay C., Dunstan N., Allen L., Bush B., Miles J. J., Ge L., Kwok H. F.* and Fry B. G.* (2018) Proteomic and functional variation within black snake venoms (Elapidae: Pseudechis). Comp Biochem Physiol C Toxicol Pharmacol 205: 53-61.
  • Perry B. I., Cooray S. E., Mendis J., Purandare K., Wijeratne A., Manjubhashini S., Dasari M., Esan F., Gunaratna I., Naseem R. A., Hoare S., Chester V., Roy A., Devapriam J., Alexander R. and Kwok H. F. (2018) Problem behaviours and psychotropic medication use in intellectual disability: a multinational cross-sectional survey. J Intellect Disabil Res 62(2):140-149.

2017

  • Wang Q., Lin W., Tang X., Li S., Guo L., Lin Y.* and Kwok H. F.* (2017) The roles of microRNAs in regulating the expression of PD-1/PD-L1 immune checkpoint. International Journal of Molecular Sciences 18(12): 2540.
  • Zhong H., Chen B., Neves H., Xing J., Ye Y., Lin Y., Zhuang G., Zhang S. D., Huang J. and Kwok H. F.* (2017) Expression of minichromosome maintenance genes in renal cell carcinoma. Cancer Management and Research 9: 637-647.
  • Wong J. P. C., Wei R., Lyu P., Tong O. L. H., Zhang S. D., Wen Q., Yuen H. F., El-Tanani M. and Kwok H. F.* (2017) Clinical and in vitro analysis of Osteopontin as a prognostic indicator and unveil its potential downstream targets in bladder cancer. International Journal of Biological Sciences 13(11): 1373-1386.
  • Kawai T., Takayanagi T., Forrester S. J., Preston K. J., Obama T., Tsuji T., Kobayashi T., Boyer, M. J., Copper H. A., Kwok H. F., Hashimoto T., Scalia R., Rizzo V., Eguchi S. (2017) Vacular ADAM17 is required for angiotensin II/β-aminopropionitrile-induced abdominal aortic aneurysm. Hypertension 70(5): 959-963.
  • Ling Y., Chen J., Guo L., Wang C., Tan W., Wen Q., Zhang S. D., Deng G.*, Lin Y.* and Kwok H. F.* (2017) β-defensin 1 expression in HCV infected liver/liver cancer: an important role in protecting HCV progression and liver cancer development. Scientific Reports 7(1): 13404.
  • Ma R., Mahadevappa R. and Kwok H. F.* (2017) Venom-based peptide therapy: insights into anti-cancer mechanism. Oncotarget 8(59): 100908-100930.
  • Guo L., Lin Y. and Kwok H. F.* (2017) The function and regulation of PD-L1 in immunotherapy. ADMET and DMPK 5(3): 159-172.
  • Mahadevappa R., Ma R. and Kwok H. F.* (2017) Venom peptides — Improving specificity for cancer therapy. Trends in Cancer 3(9): 611-614.
  • Koludarov I., Jackson T. N. W., Brouw B., Dobson J., Dashevsky D., Arbuckle K., Clemente C. J., Stockdale E. J., Cochran C., Debono J., Stephens C., Panagides N., Li B., Manchadi M. R., Violette A., Fourmy R., Hendrikx I., Nouwens A., Clements J., Martelli P., Kwok H. F. and Fry B. G. (2017) Enter the Dragon: The Dynamic and Multifunctional Evolution of Anguimorpha Lizard Venoms. Toxins 9(8): 242.
  • Wei R., Wong J.P.C. and Kwok H. F.* (2017) Osteopontin — a promising biomarker for cancer therapy. Journal of Cancer 8(12): 3173-2183.
  • Li L., Guo L., Wang Q., Liu X., Zeng Y., Wen Q., Zhang S., Kwok H. F.* and Lin Y.*, Liu J.* (2017) DAPK1 as an independent prognostic marker in liver cancer. PeerJ 5:e3568.
  • Wong J.P.C., Li B. and Kwok H. F.* (2017) Venom Peptides and Toxins – A Prospective Spearhead in Cancer Treatment. Combinatorial Chemistry High Throughput Screen 20(5): 1-19.
  • Neves H. and Kwok H. F.* (2017) In sickness and in health: The many roles of the minichromosome maintenance proteins. BBA – Reviews on Cancer 1868(1): 295-308.
  • Ye J., Yuen S. M., Murphy G., Xie R.* andKwok H. F.* (2017) Anti-Tumour Effects of a ‘Human & Mouse Cross-Reactive’ Anti-ADAM17 Antibody in a Pancreatic Cancer Model In Vivo. European Journal of Pharmaceutical Sciences 110: 62-69.
  • Debono J., Dobson J., Casewell N.R., Romilio A., Li B., Kurniawan N., Mardon K., Weisbecker V., Nouwens A., Kwok H. F., Fry B. G. (2017) Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus). Toxins 9(5): pii: E171.
  • Cipriani V., Debono J., Goldenberg J., Jackson T. N. W., Arbuckle K., Dobson J., Koludarov I., Li B., Hay C., Dunstan N., Allen L., Hendrikx I., Kwok H. F. and Fry B. G. (2017) Correlation between ontogenetic dietary shifts and venom variation in Australian brown snakes (Pseudonaja). Comp Biochem Physiol C Toxicol Pharmacol 197: 53-60.
  • Xie J. Y., Chen P. C., Zhang J. L., Gao Z. S., Neves H., Zhang S. D., Wen Q., Chen W. D., Kwok H. F.* and Lin Y.* (2017) The prognostic significance of DAPK1 in bladder cancer. PLoS One 12(4): e0175290.
  • Mahadevappa R. and Kwok H. F.* (2017) Phytochemicals – A Novel and Prominent Source of Anti-cancer Drugs against Colorectal Cancer. Combinatorial Chemistry High Throughput Screen 20: 1-19.
  • Lyu P., Zhang S. D., Yuen H. F., McCrudden C. M., Wen Q., Chan K. W. and Kwok H. F.* (2017) Identification of TWIST-interacting genes in prostate cancer. Science China Life Sciences 60(4): 386-396.
  • Xiao Y., Yan W., Guo L., Meng C., Li B., Neves H., Chen P., Li L., Huang Y., Kwok H. F.* and Lin Y.* (2017) Digitoxin Synergized with Sorafenib to Inhibit Hepatocelluar Carcinoma Cell Growth and Migration. Molecular Medicine Reports 15(2): 941-947.
  • Yuen S. M. and Kwok H. F.* (2016) Temporal establishment of neural cell identity in vivo and in vitro. Journal of Tissue Engineering and Regenerative Medicine. 11(9): 2582-2589.

2016

  • Li B., McCrudden C. M., Yuen H. F., Xi X., Lyu P., Chan K. W., Zhang S. D. and Kwok H. F.* (2016) CD133 in brain tumor: the prognostic factor. Oncotarget 8(7): 11144-11159.
  • Takayanagi T., Forrester S. J., Kawai T., Obama T., Tsuji T., Elliott K. J., Nuti E., Rossello A., Kwok H. F., Scalia R., Rizzo V. and Eguchi S. (2016)Vascular ADAM17 as a Novel Therapeutic Target in Mediating Cardiovascular Hypertrophy and Perivascular Fibrosis Induced by Angiotensin II. Hypertension 68: 949-955.
  • Shi D., Hou X., Wang L., Gao Y., Wu D., Xi X.*, Zhou M.*, Kwok H. F*., Duan J., Chen T. and Shaw C. (2016) Two Novel Dermaseptin-Like Antimicrobial Peptides with Anticancer Activities from the Skin Secretion of Pachymedusa dacnicolor. Toxins 8(5): 144.
  • Botkjaer K. A.*, Kwok H. F*., Terp M. G., Karatt-Vellatt A., Santamaria S., McCafferty J., Andreasen P. A., Itoh Y., Ditzel H. J. and Murphy G.* (2016) Development of specific affinity-matured exosite inhibitor to MT1-MMP that efficiently inhibits tumor cell invasion in vitro and metastasis in vivo. Oncotarget 7(13): 16773-16792.
  • Zhang S. D., McCrudden C. M., Yuen H. F., Leung K. L., Hong W. J. and Kwok H. F.* (2016) The association of TAZ, AXL and CTGF expression with clinicopathological parameters in colon cancer Oncology Letters 11: 1223-1229.

2015

  • Zhang S. D., Leung K. L., McCrudden C. M. and Kwok H. F.* (2015) The prognostic significance of combining VEGFA, FLT1 and KDR mRNA expressions in brain tumors. Journal of Cancer 6(9): 812-818.
  • Zhang S. D., McCrudden C. M. and Kwok H. F.* (2015) The prognostic significance of combining VEGFa, FLT1 and KDR mRNA expressions in lung cancer. Oncology Letters 10: 1893-1901.
  • Zhao D., Guo L., Neves H., Yuen H. F., Zhang S. D., McCrudden C. M., Wen Q., Zhang J., Zeng Q., Kwok H. F.* and Lin Y.* (2015) The prognostic significance of protein tyrosine phosphatase 4A2 in breast cancer. OncoTargets and Therapy 8: 1707-1717.
  • Huang Y., Zhang S. D., McCrudden C. M., Chan K. W., Lin Y. and Kwok H. F.* (2015) The prognostic significance of PD-L1 in bladder cancer. Oncology Reports 33: 3075-3084.
  • Zhang S. D., McCrudden C. M., Meng C., Lin Y* and Kwok H. F.* (2015) The significance of combining VEGFa, FLT1, and KDR expressions in colon cancer patient prognosis and predicting response to bevacizumab. OncoTargets and Therapy 8: 835-843.
  • Neves H. and Kwok H. F.* (2015) Recent advances in the field of anti-cancer immunotherapy. BBA Clinical 3: 280-288.
  • Xi X., Li B., Chen T. and Kwok H. F.* (2015) A Review on Bradykinin-Related Peptides Isolated from Amphibian Skin Secretion. Toxins 7(3): 951-970.
  • Kwok H .F.*, Zhang S. D., McCrudden C. M., Yuen H. F., Ting K. P., Wen Q., Khoo U.S.* and Chan K. Y. K.* (2015) Prognostic significance of minichromosome maintenance proteins in breast cancer. American Journal of Cancer Research 5(1): 52-71.

2014

  • Huang Y., Benaich B., Tape C. J., Kwok H. F.* and Murphy G.* (2014) Targeting the sheddase activity of ADAM17 by an anti-ADAM17 antibody D1(A12) inhibits head and neck squamous cell carcinoma cell proliferation and motility via blockage of bradykinin induced HERs transactivation. International Journal of Biological Sciences 10(7): 702-714.
  • Kwok H. F.*, Botkjaer K. A., Tape C. J., Huang Y., McCafferty J. and Murphy G. (2014) Development of a ‘mouse and human cross-reactive’ affinity-matured exosite inhibitory human antibody specific to TACE (ADAM17) for cancer immunotherapy. PEDS 27(6): 179-190.
  • van’t Wout E. F. A., Dickens J. A., van Schadewijk A., Haq I., Kwok H. F., Ordóñez A., Murphy G., Stolk J., Lomas D. A., Hiemstra P. S. and Marciniak S. J. (2014) Excess ERK signalling promotes inflammatory signalling in primary airway epithelium expressing Z α1-antitrypsin. Human Molecular Genetics 23(4): 292-241.

2010 – 2013

  • Kwok H. F.* (2013) Antibody research targeting Cathepsin S for cancer therapy. Advances in Bioscience and Biotechnology 4(4A):17-20.
  • Burden R. E., Gormley J. A., Kuehn D., Ward C., Kwok H. F., Gazdoiu M., McClurg A., Jaquin T., Johnston J. A., Scott C. J. and Olwill S. A. (2012) Inhibition of Cathepsin S by Fsn0503 enhances the efficacy of chemotherapy in colorectal carcinomas. Biochimie 94(2): 487-493.
  • Shuralev E., Quinn P., Doyle M., Duignan A., Kwok H. F., Bezos J., Olwill S. A., Gormley E., Aranaz A., Good M., Davis W. C., Clarke J. and Whelan C. (2012) Application of the Enfer chemiluminescent multiplex ELISA system for the detection of Mycobacterium bovis infection in goats. Veterinary Microbiology 154(3-4):292-297.
  • Kwok H. F.*, Buick R. J.*, Kuehn D., Gormely J. A., Doherty D., Jaquin T. J., McClurg A., Ward C., Byrne T., Jaworski J., Leung K. L., Snoddy P., McAnally C., Burden R. E., Gray B., Lowry J., Sermadiras I., Gruszka N., Courtenay-Luck N., Kissenfennig A., Scott C. J., Johnston J. A. and Olwill S. A. (2011) Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity. Molecular Cancer 10(1):147.
  • Whelan C., Shuralev E., Kwok H. F., Kenny K., Duignan A., Davis W. C. and Clarke J. (2011) Application of the Enferplex TB assay for the detection of tuberculosis positive cattle that were not detected by the SICTT. Journal of Veterinary Diagnostic Investigation 23(3):499-503.
  • Fry B. G., Winter K., Norman J. A., Roelants K., Nabuurs R. J. A., van Osch M. J. P., Teeuwisse W. M., van der Weerd L., McNaughtan J. E., Kwok H. F., Scheib H., Greisman L., Kochva E., Miller L. J., Gao F., Karas J., Scanlon D., Lin F., Kuruppu S., Shaw C., Wong L., Kuruppu S. and Hodgson W. C. (2010) Functional and structural diversification of Anguimorpha lizard venom system. Molecular & Cellular Proteomics 9(11):2369-2390.
  • Zhang Y., Wang L.,Zhou M., Zhou Z., Chen X., Chen T., Kwok H. F., Ivanyi C. and Shaw C. (2010) The structure of helokinestatin-5 and its biosynthetic precursor from Gila monster (Heloderma suspectum) venom: Evidence for helokinestatin antagonism of bradykinin-induced relaxation of rat tail artery smooth muscle. Peptides 31(8):1555-1561.
  • Kwok H. F.*, Scott C. J., Snoddy P., Buick R. J., Johnston J. A. and Olwill S. A. (2010) Profiling the humoral immune response of diagnostically sensitive mycobacterial (M. bovis) antigens in animal models. Research in Veterinary Science 89(1):41-47.
  • Whelan C., Whelan A. O., Shuralev E., Kwok H. F., Hewinson G., Clarke J. and Vordermeier H. M. (2010) Performance of the Enferplex TB assay in GB cattle and assessment of potential suitability as a DIVA test. Journal of Clinical Microbiology 17(5):813-817.
  • Kwok H. F.*, Ivanyi C., Morris A. and Shaw C. (2010) Review — Proteomic & Genomic studies on lizard venoms in the last decade. Proteomics Insights 3: 25-31.
  • Fry B.G., Roelants K., Winter K., Hodgson W. C., Griesman L., Kwok H. F., Scanlon D., Karas J., Shaw C., Wong L., Norman J. A. (2010) Novel venom proteins produced by differential domain-expression strategies in Beaded lizards and Gila monsters (genus Heloderma). Molecular Biology and Evolution 27(2): 395-407.

2002-2009

  • Kwok H. F.*, Gormley J. A., Scott C. J., Johnston J. A. and Olwill S. A. (2009) A Novel High-Throughput Technique for Identifying Monoclonal Antibodies Capable of Death Receptor Induced Apoptosis. Journal of Cell Death 2: 45-51.
  • Fry B. G., Teeuwisse W, Van Osch M. J. P., Scheib H, Winter K. L., Greisman L., Roelants K, Van der Weerd L., Clemente C. J., Giannakis E., Hodgson W. C., Luz S., Martelli P., Krishnasamy K., Kochva E., Kwok H. F., Scanlon D., Karas J., Citron D. M., Goldstein E. J. C., Mcnaughtan J. E. and Norman J. (2009) Central role for venom in predation by the Komodo Dragon and the giant extinct Megalania. PNAS 106(22): 8969-8974.
  • Whelan C., Shuralev E., O’Keeffe G., Hyland P., Kwok H. F., Snoddy P., Olwill S. A., Groll M., Watterson T., Call S., Costello E., Johnston J. A., Hamilton M .J., Davis W. C. and Clarke J. (2008) Multiplex immunoassay for the serological diagnosis of Mycobacterium bovis infected cattle. Clinical and Vaccine Immunology 15: 1834-1838.
  • Kwok H. F.* and Ivanyi C. (2008) Venom acquisition from helodermatid lizards. Herpetological Review 39(2): 179-181.
  • Kwok H. F.*, Chen T., Ivanyi C. and Shaw C. (2008) DNA in Amphibian and Reptile Venom Permits Access to Genomes Without Specimen Sacrifice. Genomics Insights 1: 17-24.
  • Kwok H. F.*, Chen T., O’Rourke M., Ivanyi C., Hirst D. and Shaw C. (2008) Helokinestatin: a novel bradykinin B2 receptor antagonist decapeptide from lizard venom. Peptides 29: 65-72.
  • Chen T., Kwok H. F., Ivanyi C. and Shaw C. (2006) Isolation and cloning of exendin precursor cDNAs from single samples of venom from the Mexican beaded lizard (Heloderma horridum) and the Gila monster (Heloderma suspectum). Toxicon 47(3): 288-295.
  • Chen T., Folan R., Kwok H. F., Bjourson A. J. and Shaw C. (2003) Isolation of scorpion (Androctonus amoreuxi) putative alpha neurotoxin and parallel cloning of their respective cDNAs from a single sample of venom. Regulatory Peptide 115(2): 115-121.
  • Chen T., Bjourson A. J., Orr D. F., Kwok H. F., Ping F., Ivanyi C. and Shaw C. (2002) Unmasking venom gland transcriptomes in reptile venoms. Analytical Biochemistry 311: 152-156.

Book/Book Chapters:

  • Kwok H. F. (Ed.)* (2019) Venom toxins as potential targeted therapy (pp. 1-167). Basel, Switzerland: Multidisciplinary Digital Publishing Institute (MDPI).
  • Fry B. G., Roelants K., Jackson T. N. W., Takacs Z., Reeks T. and Kwok H. F.* (2015) Chapter 18 B-Type natriuretic peptides. In Bryan Fry (Ed.), Venomous Reptiles and Their Toxins (pp. 312-317). Oxford, UK: Oxford University Press.
  • Fry B. G., Roelants K., Jackson T. N. W., Takacs Z., Reeks T. and Kwok H. F.* (2015) Chapter 11 Exendin peptides. In Bryan Fry (Ed.), Venomous Reptiles and Their Toxins (pp. 247-254). Oxford, UK: Oxford University Press.

*corresponding author