2025-09-15T18:08:36+08:002022-09-09|
Contact Information
Title
Assistant Professor
Office
(Address) E12-3030 / (Phone) +853 8822 4771
Lab
(Address) E12-1066
Team Office
(Address) E12-1028 / (Phone) +853 8822 2914, 8822 4222
Email
beili@um.edu.mo
Consultation Hours

Mon, Tue 16:00-17:00

Teaching

HSCI1001 General Chemistry Lab 

Education
PhD The University of Queensland, Australia (2019)
MMS Beijing University of Chemical Technology, China (2015)
BSc Beijing University of Chemical Technology, China (2011)
Position
07/2025 – Present Assistant Professor, Faculty of Health Sciences, University of Macau
07/2022 – 07/2025 Research Assistant Professor, Faculty of Health Sciences, University of Macau
07/2020 – 07/2022 Postdoctoral Fellow, Faculty of Health Sciences, University of Macau
Research Interests
  1. Designing new adjuvants to improve tumor antigen processing, presentation, and recognition.
  2. Initiating antimicrobial immunity to enhance tumor immunogenicity.
  3. Fabricating new contrast agents for early cancer diagnosis.
  4. Investigating immunopeptides using computational biology methods

See also https://scholar.google.com/citations?hl=en&user=sVaL7RUAAAAJ&view_op=list_works&sortby=pubdate
Representative Publications
As a first author (including co-first author#)/corresponding author (*):

  1. Yan Tan, Bei Li*, Yunlu Dai*, A personalized 3D-printed cervical plug advances ART outcome. Cell Biomaterials 2025, 1, 100102.
  2. Wenxi Li, Hao Tian, Ziliang Yan, Xinying Yu, Bei Li*, Yunlu Dai*, Magnesium-phenolic nanoeditor refining gliomatous T cells for metalloimmunotherapy. ACS Nano 2025, 19, 1222.
  3. Bei Li#, Yan Tan#, Josh Haipeng Lei#, Min Deng, Xinwang Yu, Lin He, Chu-Xia Deng*, Yunlu Dai*, Alkaline adjuvant drives antigen cross-presentation by macrophages and potentiates radiotherapeutic tumor immunogenicity. Advanced Materials 2025, 38, 2416690.
  4. Guohao Wang#, Jie Yan#, Hao Tian#, Bei Li*, Xinying Yu, Yuzhao Feng, Wenxi Li, Songtao Zhou, Yunlu Dai*, Dual-epigenetically relieving the MYC-correlated immunosuppression via an advanced nano-radiosensitizer potentiates cancer immuno-radiotherapy. Advanced Materials 2024, 36, 2312588.
  5. Xinying Yu, Bei Li*, Jie Yan, Wenxi Li, Hao Tian, Guohao Wang, Songtao Zhou, Yunlu Dai*, Cuproptotic nanoinducer-driven proteotoxic stress potentiates cancer immunotherapy by activating the mtDNA-cGAS-STING signaling. Biomaterials 2024, 307, 122512.
  6. Bei Li#, Guohao Wang#, Kai Miao#, Aiping Zhang, Liangyu Sun, Xinwang Yu, Josh Haipeng Lei, Lisi Xie, Jie Yan, Wenxi Li, Chu-Xia Deng*, Yunlu Dai*, Fueling sentinel node via reshaping cytotoxic T lymphocytes with a flex-patch for post-operative immuno-adjuvant therapy. Nature Communications 2023, 14, 2518.
  7. Jie Yan#, Wenxi Li#, Hao Tian#, Bei Li*, Xinying Yu, Guohao Wang, Wei Sang, Yunlu Dai*, Metal-phenolic nanomedicines regulate T-cell antitumor function for sono-metabolic cancer therapy. ACS Nano 2023, 33, 2213425.
  8. Guohao Wang#, Bei Li#, Hao Tian, Lisi Xie, Jie Yan, Wei Sang, Jie Li, Zhan Zhang, Wenxi Li, Yunlu Dai*, A metal-phenolic nanocoordinator launches radiotherapeutic cancer pyroptosis through an epigenetic mechanism. Advanced Functional Materials 2023, 33, 2213425.
  9. Guohao Wang#, Lisi Xie#, Bei Li#, Wei Sang, Jie Yan, Jie Li, Wenxi Li, Zhan Zhang, Ye Tian, Yunlu Dai*, A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis. Nature Communications 2021, 12, 5733.
  10. Jie Li#, Lisi Xie#, Bei Li#, Chao Yin, Guohao Wang, Wei Sang, Wenxi Li, Hao Tian, Zhan Zhang, Xunjun Zhang, Quli Fan*, Yunlu Dai*, Engineering a hydrogen sulfide-based nanomodulator to normalize hyperactive photothermal immunogenicity for combination cancer therapy. Advanced Materials 2021, 33, 2008481.
  11. Jie Yan#, Bei Li#, Piaoping Yang*, Jun Lin*, Yunlu Dai*, Progress in light-responsive lanthanide nanoparticles toward deep tumor theranostics. Advanced Functional Materials 2021, 31, 2104325.
  12. Bei Li, Guanyu Hao, Bing Sun, Zi Gu*, Zhi Ping Xu*, Engineering a therapy-induced “immunogenic cancer cell death” amplifier to boost systemic tumor elimination. Advanced Functional Materials 2020, 30, 1909745.
  13. Bei Li, Jie Tang, Weiyu Chen, Guanyu Hao, Nyoman Kurniawan, Zi Gu*, Zhi Ping Xu*, Novel theranostic nanoplatform for complete mice tumor elimination via MR imaging-guided acid-enhanced photothermo-/chemo-therapy. Biomaterials 2018, 177, 40.
  14. Bei Li, Zi Gu*, Nyoman Kurniawan, Weiyu Chen, Zhi Ping Xu*, Manganese-based layered double hydroxide nanoparticles as a T1-MRI contrast agent with ultrasensitive pH response and high relaxivity. Advanced Materials 2017, 29, 1700373.
  15. Bei Li, Yufei Zhao, Shitong Zhang, Wa Gao, Min Wei*, Visible-light-responsive photocatalysts toward water oxidation based on NiTi-layered double hydroxide/reduced graphene oxide composite materials. ACS Applied Materials & Interfaces, 2013, 5, 10233.
  16. Xinyi Wang, Iek Man Lei, Bei Li*, Yunlu Dai*, Progress in extracellular vesicle@STING towards immune regulation. Chinese Chemical Letters 2025, 110990.
  17. Guifen Li, Yulan Gu, Rui Ren, Sitan Li*, Houen Zhu, Dongdong Xue, Xiangyi Kong, Ziyi Zheng, Nuo Liu, Bei Li*, Jiangwei Zhang*, Efficient reduction of CO2 and inhibition of hydrogen precipitation by polyoxometalate photocatalyst modified with the metal Mn. Nanoscale 2024, 16, 12550.
  18. Jiaxin Li#, Bei Li#, Jikang Wang, Lei He*, Yufei Zhao*, Recent advances in layered double hydroxides and their derivatives for biomedical applications. Acta Chimica Sinica 2021, 79, 238.

As a co-author:

  1. Jie Liu, Bei Li, Li Li, Xin Ming, Zhi Ping Xu, Advances in nanomaterials for immnotherapeutic improvement of cancer chemotherapy. Small 2024, 20, 2403024.
  2. Zhan Zhang, Bei Li, Lisi Xie, Wei Sang, Hao Tian, Jie Li, Guohao Wang, Yunlu Dai*, Metal-phenolic network-enabled lactic acid consumption reverses immunosuppressive tumor microenvironment for sonodynamic therapy. ACS Nano 2021, 15, 16934.
  3. Zhenbang Cao, Bei Li, Luyao Sun, Li Li, Zhi Ping Xu, Zi Gu*, 2D layered double hydroxide nanoparticles: recent progress toward preclinical/clinical nanomedicine. Small Methods 2020, 4, 1900343.
  4. Jie Tang, Bei Li, Christopher B Howard, Stephen M Mahler, Kristofer J Thurecht, Yilun Wu, Leaf Huang, Zhi Ping Xu*, Multifunctional lipid-coated calcium phosphate nanoplatforms for complete inhibition of large triple negative breast cancer via targeted combined therapy. Biomaterials 2019, 216, 119232.
  5. Ye Tian, Hao Tian, Bei Li, Chuanliang Feng, Yunlu Dai*, An ultrasound-triggered STING pathway nanoagonist for enhanced chemotherapy-induced immunogenic cell death. Small 2024, 20, 2309850.
  6. Weiyu Chen, Huali Zuo, Bei Li, Chengcheng Duan, Barbara Rolfe, Bing Zhang, Timothy J Mahony, Zhi Ping Xu*, Clay nanoparticles elicit long-term immune responses by forming biodegradable depots for sustained antigen stimulation. Small 2018, 14, 1704465.
  7. Wenxi Li, Jie Yan, Hao Tian, Bei Li, Guohao Wang, Wei Sang, Zhan Zhang, Xuanjun Zhang, Yunlu Dai*, A platinum@polymer-catechol nanobraker enables radio-immunotherapy for crippling melanoma tumorigenesis, angiogenesis, and radioresistance. Bioactive Materials 2023, 22, 34-46.
  8. Jianping Liu, Yilun Wu, Changkui Fu, Bei Li, Li Li, Run Zhang, Tiefeng Xu, Zhi Ping Xu*, Charge reversion simultaneously enhances tumor accumulation and cell uptake of layered double hydroxide nanohybrids for effective imaging and therapy. Small 2020, 16, 2002115.
  9. Zhan Zhang, Wei Sang, Lisi Xie, Wenxi Li, Bei Li, Jie Li, Hao Tian, Zhen Yuan, Qi Zhao, Yunlu Dai*, Polyphenol-based nanomedicine evokes immune activation for combination cancer treatment. Angewandte Chemie International Edition 2021, 60, 1967.
  10. Jie Yan, Guohao Wang, Lisi Xie, Hao Tian, Jie Li, Bei Li, Wei Sang, Wenxi Li, Zhan Zhang, Yunlu Dai*, Engineering Radiosensitizer-Based Metal-Phenolic Networks Potentiate STING Pathway Activation for Advanced Radiotherapy. Advanced Materials 2022, 34, 2105783.
  11. Mengjie Zhang, Abid Hussain, Bo Hu, Haiyin Yang, Chunhui Li, Shuai Guo, Xiaofeng Han, Bei Li, Yuhong Cao, Hang Chi, Yuhua Weng, Cheng-Feng Qin, Yuanyu Huang*, Atavistic strategy for the treatment of hyperuricemia via ionizable liposomal mRNA. Nature Communications 2024, 15, 6463.
  12. Lisi Xie, Jie Li, Guohao Wang, Wei Sang, Mengze Xu, Wenxi Li, Jie Yan, Bei Li, Zhan Zhang, Qi Zhao, Zhen Yuan, Quli Fan, Yunlu Dai*, Phototheranostic metal-phenolic networks with antiexosomal PD-L1 enhanced ferroptosis for synergistic immunotherapy. Journal of the American Chemical Society 2022, 144, 787.

Full publications list
Research Grants
2023 – 2025 The Science and Technology Development Fund, No. FDCT 0006/2023/ITP1
2022 – 2024 National Natural Science Foundation of China (NSFC), No. 32101069
2023 University of Macau, MoE FSCPO Fund (SP2023-00001-FSCPO)
Patents
  1. Min Wei*, Bei Li, Yufei Zhao, Xue Duan, Visible light response of NiTi-LDH/RGO composite photocatalyst and its preparation method. Chinese Patent: 201210440012.7
  2. Min Wei*, Yufei Zhao, Bei Li, Wa Gao, Xue Duan, Synthesis of NiTi-layered double hydroxide nanosheets. Chinese Patent: 201210434511.5
  3. Min Wei*, Yufei Zhao, Wa Gao, Bei Li, Visible light response of ZnTi-LDH composite photocatalyst and its preparation method. Chinese Patent: 201210434472.9
Awards
2023 Outstanding reviewer, Journal of Nanobiotechnology (IF = 12.6)
2019 Dean’s award for outstanding higher degree by research theses, The University of Queensland, Australia
2015 – 2019 International postgraduate research scholarship (IPRS, Top 1‰) and The University of Queensland centennial scholarship (UQCent), Australia
2017 Chinese government award for outstanding self-financed students abroad (Top 1‰), Australia
2017 Donald Tugby prize in nanotechnology (for best publication), The University of Queensland, Australia
2016 International and Domestic travel grant, The University of Queensland, Australia
2015 Outstanding graduate, Beijing University of Chemical Technology, China
2015 Outstanding Thesis Award, Beijing University of Chemical Technology, China
2013 National scholarship for outstanding graduate student, China
2007 – 2011 Excellent Undergraduate Scholarships, Beijing University of Chemical Technology, China
Professional Activities
2023 – Present Academic Editor of the Exploration Journal
2024 – Present Editorial Board Member of International Journal of Molecular Sciences
2024 – Present Editorial Board Member of the Scientific Reports Journal
2023 – Present Junior Editorial Board Member of Microstructures Journal
Reviewers of Journals (e.g., Sci. Adv., Adv. Mater., Biomaterials, Explorations, Theranostics, etc.)
2024 1st Editorial Board Meeting of Microstructures, Hainan, China (Invited Speaker)
2023 13th International Nanomedicine Conference, Sydney, Australia (Session Chair and Invited Speaker)
2023 Summit on Functional Nanomaterials for Energy and Beyond, China (Session Chair and Invited Speaker)
2018 11th European and Global Summit for Clinical Nanomedicine, Targeted Delivery and Precision Medicine, Basel, Switzerland (Invited Speaker)
2018 International Conference on Nanomedicine and Nanobiotechnology, Rome, Italy (Speaker)