2021-08-26T11:47:58+08:002019-11-29|
Contact Information
Education
PhD Michigan State University
BS Michigan State University
Positions
2014-present Senior Instructor, Faculty of Health Sciences, University of Macau
2008-2014 Research Scientist, Stem Cell Institute, UConn Health Center
2003-2008 Post-doctoral Fellow, UConn Health Center
Research Interests
  • Molecular circuitry of induced Pluripotent Stem Cells (iPSC) reprogramming
  • Molecular mechanisms for Marfan Syndrome (MS), a genetic disease manifested in defects of mesenchymal lineages and connective tissues
  • Regulatory mechanisms by which human Embryonic Stem Cells (hESCs) differentiate into Mesenchymal Stem Cells (MSCs)
  • Post-transcriptional regulations in hESC/iPSC self-renewal and differentiation
Representative Publications
  1. Park J.W.#, Fu S.Y., Huang, B.R., Xu R.H., 2020 Alternative splicing in mesenchymal stem cells differentiation, Stem cells, [published online ahead of print, 2020 Jul 6]. Stem Cells. 2020;10.1002/stem.3248. doi:10.1002/stem.3248
  2. Park J.W.#, Yang J., Xu R.H., 2018 PAX6 alternative splicing and corneal development. Stem Cells and Development, 27(6):367-377
  3. Park J.W., Yan L., Stoddard C., Wang X.F., Yue Z.C., Crandall L., Robinson T., Chang Y.X., Denton K., Li E.Q., Jiang B., Zhang Z.W., Martins-Taylor K., Yee S.P., Yue L.X., Xu, R.H., 2017 Recapitulating and correcting Marfan Syndrome in a cellular model. Int J Biol Sci, 13(5):588-603
  4. Wang J.W.*., Park J.W.*, Drissi H., Wang X., Xu R.H. Epigenetic regulation of miR-302 by JMJD1C inhibits neural differentiation of human embryonic stem cells. J Biol Chem,  289(4):2384-95
  5. Olson S., Blanchette M., Park J.W., Savva Y., Yeo G., Yeakley J., Rio D., and Graveley R.  2007.  A regulator of Dscam mutually exclusive splicing fidelity. Nature Struct and Mol Biol, 14:1134 – 1140
  6. Yang L., Park J.W., and Graveley B.R. 2007. Splicing from the outside in.  Molecular Cell, 27:861-2 
  7. Park J.W., Parisky K., Celotto A., Reenan R.A., and Graveley B.R.   Identification of alternative splicing regulators by RNA interference in Drosophila. Proc Natl Acad Sci USA, 101:15974-15979. Epub 2004 Oct 18.
  8. Park J.W., Voss P., Grabski S., Wang J.L., and Patterson R.J.  2001.  Association of galectins-1 and galectins-3 with Gemin4 in complexes containing the SMN protein.  Nucleic Acids Res, 27(17):3595-3602
Full publications list