HSCI7001 Artificial Intelligence in Medicine
|PhD||University of Wisconsin-Madison (Immunology), 2001|
|MEng||Cornell University (Computer Science), 2002|
|BSc||Peking University (Biochemistry & Molecular Biology), 1996|
|2022-present||Associate Professor, Faculty of Health Sciences, University of Macau|
|2017-2022||Principle Investigator, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, PR China|
|2011-2017||Principle Investigator, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, PR China|
|2006-2011||Research Associate, La Jolla Institute of Allergy & Immunology, La Jolla, CA, USA|
|2003-2006||Postdoctoral Researcher, Computational Systems Biology Laboratory, University of Georgia, Athens, GA, USA|
|Our research interests are to obtain a quantitative understanding of the dynamics of tumorigenesis, particularly metastasis; and to develop mathematical characterizations of the common principles underlying tumor heterogeneity. We also have a strong translational interest to develop effective therapies for cancer driven by systems biology and data science.
Currently our research focuses on three directions. The first direction is computational systems biology of cancer. We are combining computational and systems biology strategies to understand how dynamic and heterogeneous regulatory networks drive metastasis, and to decipher the quantitative rules that dictate how certain combination of mutations could drive tumorigenesis. The second area of active research is cancer data science. Currently we are interested in developing novel algorithms for single-cell omics data analysis, regulatory network inference, and multi-modal omics and clinical data integration. Finally, we are actively pursuing translation research to develop novel biomarkers for early cancer/metastasis detection, and combinatorial therapeutic strategies to overcome drug resistance.
|Full Publications List|
|Hundred Talents Program of Chinese Academy of Sciences (2013)|